Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.
about
LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAsMany roads lead to a broken heart: the genetics of dilated cardiomyopathy.DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repairMitochondriaMitochondrial DNA mutations in human diseaseEffects of hypothalamic neurodegeneration on energy balance.Rescue of Heart Failure by Mitochondrial RecoveryElectron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsAn experimental approach to study the function of mitochondria in cardiomyopathyHeart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategiesLoss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activitySuccinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutantMitochondria and oxidative stress in heart agingThe Role of Exercise in Cardiac Aging: From Physiology to Molecular MechanismsThe variability of the harlequin mouse phenotype resembles that of human mitochondrial-complex I-deficiency syndromesA mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathyMitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factorMitochondrial DNA polymerase gamma is essential for mammalian embryogenesisReduced activity of mtTFA decreases the transcription in mitochondria isolated from diabetic rat heartIncreased in vivo apoptosis in cells lacking mitochondrial DNA gene expressionA crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathyPLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasisTransient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells.Isolation of rat mitochondrial transcription factor A (r-Tfam) cDNA.Proteomic analysis of mitochondria reveals a metabolic switch from fatty acid oxidation to glycolysis in the failing heart.The role of mitochondrial DNA mutations in mammalian agingRevolution in mitochondrial medicine.Reverse genetic studies of mitochondrial DNA-based diseases using a mouse model.A nuclear-mitochondrial DNA interaction affecting hearing impairment in miceDisruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.Defective DNA replication impairs mitochondrial biogenesis in human failing heartsMitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice.Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.Mitochondrial encephalomyopathy.Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory networkMuscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy.Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species productionDiscovering altered genomic expression patterns in heart: transcriptome determination by serial analysis of gene expression.
P2860
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P2860
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@en
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@nl
type
label
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@en
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@nl
prefLabel
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@en
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@nl
P2093
P50
P356
P1433
P1476
Dilated cardiomyopathy and atr ...... chondrial DNA gene expression.
@en
P2093
Brüning JC
Clayton DA
Wilhelmsson H
P2888
P304
P356
10.1038/5089
P407
P577
1999-01-01T00:00:00Z