Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.
about
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiencyGain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertensionAn african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severityBeta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanismsMechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle DisordersInteracting influence of diuretics and diet on BK channel-regulated K homeostasisBK channels: multiple sensors, one activation gateFunction and regulation of large conductance Ca(2+)-activated K+ channel in vascular smooth muscle cellsIon channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approachesHypoxia and ischemia-reperfusion: a BiK contribution?Post-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxiaMinding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicitySplicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscleThe BK channel accessory beta1 subunit determines alcohol-induced cerebrovascular constrictionCerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agentStructural basis for calcium and magnesium regulation of a large conductance calcium-activated potassium channel with β1 subunitsAstrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction.A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans.Two distinct signaling pathways for regulation of spontaneous local Ca2+ release by phospholipase C in airway smooth muscle cells.Propofol increases the Ca2+ sensitivity of BKCa in the cerebral arterial smooth muscle cells of mice.Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscleImpairment in function and expression of transient receptor potential vanilloid type 4 in Dahl salt-sensitive rats: significance and mechanismSodium and potassium regulate endothelial phospholipase C-γ and Bmx.Altered L-type Ca2+ channel activity contributes to exacerbated hypoperfusion and mortality in smooth muscle cell BK channel-deficient septic mice.Epigenetic upregulation of large-conductance Ca2+-activated K+ channel expression in uterine vascular adaptation to pregnancyCDK5 interacts with Slo and affects its surface expression and kinetics through direct phosphorylationThe regulation of BK channel activity by pre- and post-translational modifications.Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.Common charge-shift mutation Glu65Lys in K+ channel β₁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal diseaseBK channel activators and their therapeutic perspectivesInvited review: mechanisms of calcium handling in smooth muscles.Ion channels in smooth muscle: regulators of intracellular calcium and contractility.11,12-EET stimulates the association of BK channel α and β(1) subunits in mitochondria to induce pulmonary vasoconstriction.Novel mechanisms contributing to cerebral vascular dysfunction during chronic hypertension.Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signalingLarge-conductance Ca2+-activated K+ channel beta1-subunit knockout mice are not hypertensiveWestern blot analysis of BK channel β1-subunit expression should be interpreted cautiously when using commercially available antibodies.Low Na, high K diet and the role of aldosterone in BK-mediated K excretion.Impact of heme and heme degradation products on vascular diameter in mouse visual cortexTuning magnesium sensitivity of BK channels by mutations.
P2860
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P2860
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca
@nl
Mice with disrupted BK channel ...... g and elevated blood pressure.
@en
type
label
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca
@nl
Mice with disrupted BK channel ...... g and elevated blood pressure.
@en
prefLabel
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca
@nl
Mice with disrupted BK channel ...... g and elevated blood pressure.
@en
P2093
P356
P1433
P1476
Mice with disrupted BK channel ...... g and elevated blood pressure.
@en
P2093
Faulhaber J
Fürstenau M
Gollasch M
Waldschütz R
P304
P356
10.1161/01.RES.87.11.E53
P577
2000-11-01T00:00:00Z