Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing.
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Fibroblast morphogenesis on 3D collagen matrices: the balance between cell clustering and cell migrationRelationships among parvalbumin-immunoreactive neuron density, phase-locked gamma oscillations, and autistic/schizophrenic symptoms in PDGFR-β knock-out and control miceCognitive and socio-emotional deficits in platelet-derived growth factor receptor-β gene knockout mice.Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matricesPromigratory and procontractile growth factor environments differentially regulate cell morphogenesisThe S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation.Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.PDGFR-β as a positive regulator of tissue repair in a mouse model of focal cerebral ischemiaCXCR4 antagonist AMD3100 accelerates impaired wound healing in diabetic mice.A common phosphotyrosine signature for the Bcr-Abl kinase.Hsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing.PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation.Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.PDGFRα plays a crucial role in connective tissue remodeling.PKCδ impaired vessel formation and angiogenic factor expression in diabetic ischemic limbs.Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programsInterferon-γ blocks signalling through PDGFRβ in human brain pericytesPericyte-fibroblast transition promotes tumor growth and metastasis.Promoting Diabetic Wound Therapy Using Biodegradable rhPDGF-Loaded Nanofibrous Membranes: CONSORT-Compliant ArticleChanges in Otx2 and parvalbumin immunoreactivity in the superior colliculus in the platelet-derived growth factor receptor-β knockout miceA blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae.Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12SHIP2 and its involvement in various diseases.Deconstructing fibrosis research: do pro-fibrotic signals point the way for chronic dermal wound regeneration?Pathogenetic significance and possibility as a therapeutic target of platelet derived growth factor.Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblastsPlatelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts.Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts.Connective tissue growth factor differentially binds to members of the cystine knot superfamily and potentiates platelet-derived growth factor-B signaling in rabbit corneal fibroblast cellsMouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury.Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor β-receptor lacking mice.Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation.PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke.Renal Interstitial Platelet-Derived Growth Factor Receptor-β Cells Support Proximal Tubular Regeneration.Hydrogen sulfide suppresses transforming growth factor-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts.Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling.Effects of platelet-derived growth factor isoforms on plasminogen activation by periodontal ligament and gingival fibroblasts.The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model.Endothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1
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P2860
Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@en
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@nl
type
label
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@en
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@nl
prefLabel
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@en
Deletion of the PDGFR-beta gen ...... s important for wound healing.
@nl
P2093
P356
P1476
Deletion of the PDGFR-beta gen ...... ns important for wound healing
@en
P2093
Hemragul Sabit
Maiko Naito
Makoto Kawaguchi
Masakiyo Sasahara
Masashi Kobayashi
Shin Ishizawa
Takeshi Oya
Toshiyasu Sasaoka
Yo-Ichi Nabeshima
Yoko Ishii
P304
P356
10.1074/JBC.M413081200
P407
P577
2004-12-06T00:00:00Z