Mutations in TREM2 lead to pure early-onset dementia without bone cysts. - Wikidata - awgldk - TriplyDB

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

http://www.wikidata.org/entity/Q52587424

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Variant of TREM2 Associated with the Risk of Alzheimer's Disease CAS proteins in normal and pathological cell growth control Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system Novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement Genomic variants, genes, and pathways of Alzheimer's disease: An overview.Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.Coding variants in TREM2 increase risk for Alzheimer's disease Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease.A review of the diverse genetic disorders in the Lebanese population: highlighting the urgency for community genetic services.Differential modulation of TREM2 protein during postnatal brain development in mice.Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.Functional differences between microglia and monocytes after ischemic stroke.TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer's Disease and Schizophrenia.Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells.TREM2 is associated with the risk of Alzheimer's disease in Spanish population TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.TREM2 in Alzheimer's disease.Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation.Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease.Review: The genetics of Alzheimer's disease; putting flesh on the bones.Microglia and inflammation: conspiracy, controversy or control?The Role of TREM2 in Alzheimer's Disease and Other Neurological Disorders.The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E.TREM2 in Neurodegenerative Diseases.The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases TREM2-Ligand Interactions in Health and Disease.The clinical spectrum of sporadic and familial forms of frontotemporal dementia.Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation.Targeted sequencing approach to identify genetic mutations in Nasu-Hakola disease.TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.A case of TREM2 mutation presenting with features of progressive non-fluent aphasia and without bone involvement.Sporadic adult-onset leucodystrophy with axonal spheroids and pigmented glia with no mutations in the known targeted genes.Variable expression of microglial DAP12 and TREM2 genes in Nasu-Hakola disease.

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Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

http://www.wikidata.org/entity/Q52587424

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh-hant

name

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@en

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@nl

type

label

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@en

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@nl

prefLabel

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@en

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

@nl

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Mutations in TREM2 lead to pure early-onset dementia without bone cysts.

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André Mégarbané

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Anne Bergougnoux

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Eliane Chouery

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Jean-Louis Serre

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Salam Koussa

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Valérie Delague

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E194-204

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scholarly article

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10.1002/HUMU.20836

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9

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29

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2008-09-01T00:00:00Z

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18546367

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