Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut.
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Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogasterTissue communication in regenerative inflammatory signaling: lessons from the fly gutConserved mechanisms of tumorigenesis in the Drosophila adult midgutEGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration.A deregulated intestinal cell cycle program disrupts tissue homeostasis without affecting longevity in Drosophila.Epithelial regeneration and cancer: news from the Src front.c-Src drives intestinal regeneration and transformation.Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries.Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.Accumulation of differentiating intestinal stem cell progenies drives tumorigenesisNiche appropriation by Drosophila intestinal stem cell tumours.Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila.Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration.JAK-STAT signaling in stem cells and their niches in Drosophila.The Drosophila JAK-STAT pathway in blood cell formation and immunity.Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.Intestinal stem cell response to injury: lessons from Drosophila.Drosophila hematopoiesis under normal conditions and in response to immune stress.Iro/IRX transcription factors negatively regulate Dpp/TGF-β pathway activity during intestinal tumorigenesis.Interferon-α reduces the gefitinib sensitivity of human non-small cell lung cancer.Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.Activation of Janus kinase 1 confers poor prognosis in patients with non-small cell lung cancer.Colorectal cancer: A powerful model.APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation.Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila.Wnt Signalling in Intestinal Stem Cells: Lessons from Mice and Flies.APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway.Myc function in Drosophila.Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine.Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation.Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective.Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations.
P2860
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P2860
Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut.
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name
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@en
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@nl
type
label
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@en
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@nl
prefLabel
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@en
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@nl
P50
P356
P1433
P1476
Non-autonomous crosstalk betwe ...... n the Drosophila adult midgut.
@en
P2093
Kevin Myant
P304
P356
10.1242/DEV.078261
P407
P577
2012-12-01T00:00:00Z