Effects of sequestration on signal transduction cascades.
about
Open cascades as simple solutions to providing ultrasensitivity and adaptation in cellular signalingSmall RNAs establish delays and temporal thresholds in gene expressionDose response relationship in anti-stress gene regulatory networksModeling networks of coupled enzymatic reactions using the total quasi-steady state approximationOperating regimes of signaling cycles: statics, dynamics, and noise filteringA hidden feedback in signaling cascades is revealedSwitches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination systemThe Goodwin model: behind the Hill functionLoads bias genetic and signaling switches in synthetic and natural systemsPositive feedback promotes oscillations in negative feedback loopsA systems model of phosphorylation for inflammatory signaling eventsEnzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling NetworksUltrasensitive response motifs: basic amplifiers in molecular signalling networks.Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspectiveReciprocal regulation as a source of ultrasensitivity in two-component systems with a bifunctional sensor kinase.Positional information generated by spatially distributed signaling cascades.Coupled stochastic spatial and non-spatial simulations of ErbB1 signaling pathways demonstrate the importance of spatial organization in signal transductionNoise management by molecular networksLigand depletion in vivo modulates the dynamic range and cooperativity of signal transduction.A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasisA combination of multisite phosphorylation and substrate sequestration produces switchlike responses.Paradoxical results in perturbation-based signaling network reconstructionSignaling properties of a covalent modification cycle are altered by a downstream target.Biosensor architectures for high-fidelity reporting of cellular signaling.The role of dynamic stimulation pattern in the analysis of bistable intracellular networksHow molecular competition influences fluxes in gene expression networks.Bell-shaped and ultrasensitive dose-response in phosphorylation-dephosphorylation cycles: the role of kinase-phosphatase complex formation.Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade.Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior.Branched motifs enable long-range interactions in signaling networks through retrograde propagationUltrasensitivity in phosphorylation-dephosphorylation cycles with little substrateA generalised enzyme kinetic model for predicting the behaviour of complex biochemical systemsUltrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback.Ultrasensitive Negative Feedback Control: A Natural Approach for the Design of Synthetic Controllers.Signaling cascades transmit information downstream and upstream but unlikely simultaneously.Minimal oscillating subnetwork in the Huang-Ferrell model of the MAPK cascade.Use of virtual cell in studies of cellular dynamics.On sensitivity amplification in intracellular signaling cascadesNetwork dynamics.Spatially distributed cell signalling.
P2860
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P2860
Effects of sequestration on signal transduction cascades.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Effects of sequestration on signal transduction cascades.
@en
Effects of sequestration on signal transduction cascades.
@nl
type
label
Effects of sequestration on signal transduction cascades.
@en
Effects of sequestration on signal transduction cascades.
@nl
prefLabel
Effects of sequestration on signal transduction cascades.
@en
Effects of sequestration on signal transduction cascades.
@nl
P2860
P50
P1433
P1476
Effects of sequestration on signal transduction cascades.
@en
P2093
Frank J Bruggeman
Hanspeter Herzel
P2860
P304
P356
10.1111/J.1742-4658.2006.05105.X
P407
P577
2006-03-01T00:00:00Z