Loss of suppressor-of-fused function promotes tumorigenesis.
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Pediatric medulloblastoma - update on molecular classification driving targeted therapiesArsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorRhabdomyosarcoma: Advances in Molecular and Cellular BiologyHedgehog signaling pathway in ovarian cancerCross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenanceGenome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibitionVismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.Cerebellum development and medulloblastomaDevelopment and cancer of the cerebellumArsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulationRecent patents for Hedgehog pathway inhibitors for the treatment of malignancy.Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.NL-103, a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations.Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expressionConcerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological featuresSuppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosisModulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.Molecular subgroups of medulloblastoma.Clinical implications of hedgehog signaling pathway inhibitorsThe hedgehog/Gli signaling paradigm in prostate cancerLoss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant miceMURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.Specific inhibition of the transcription factor Ci by a cobalt(III) Schiff base-DNA conjugate.Probing for a deeper understanding of rhabdomyosarcoma: insights from complementary model systems.Synthesis, Molecular Mechanism and Pharmacokinetic Studies of New Epoxy Lignan-Based Derivatives.Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth.A mouse model of rhabdomyosarcoma originating from the adipocyte lineage.Loss of SUFU function in familial multiple meningioma.Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient miceCooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.Implications of hedgehog signaling antagonists for cancer therapy.Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer.Cerebellum Development and Tumorigenesis: A p53-Centric Perspective.Signaling pathway and molecular subgroups of medulloblastoma.Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice.Medulloblastoma stem cells.
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P2860
Loss of suppressor-of-fused function promotes tumorigenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Loss of suppressor-of-fused function promotes tumorigenesis.
@en
Loss of suppressor-of-fused function promotes tumorigenesis.
@nl
type
label
Loss of suppressor-of-fused function promotes tumorigenesis.
@en
Loss of suppressor-of-fused function promotes tumorigenesis.
@nl
prefLabel
Loss of suppressor-of-fused function promotes tumorigenesis.
@en
Loss of suppressor-of-fused function promotes tumorigenesis.
@nl
P2093
P2860
P356
P1433
P1476
Loss of suppressor-of-fused function promotes tumorigenesis.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210467
P407
P50
P577
2007-04-23T00:00:00Z