Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. - Wikidata - awgldk - TriplyDB

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

http://www.wikidata.org/entity/Q53334281

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"Sentinel" circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4 The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation Extracellular Superoxide Dismutase: Growth Promoter or Tumor Suppressor?Oncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer Cells The FHIT gene product: tumor suppressor and genome "caretaker"A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer Cancer stem cells: the lessons from pre-cancerous stem cells RAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells PI3K pathway alterations in cancer: variations on a theme Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells p21 in cancer: intricate networks and multiple activities Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.Suppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics.Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.Minireview: physiological and pathological actions of RAS in the ovary.A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation ERBB2 increases metastatic potentials specifically in androgen-insensitive prostate cancer cells.The inflammatory network: bridging senescent stroma and epithelial tumorigenesis.Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras.Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance Selective activation of p53-mediated tumour suppression in high-grade tumours.Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.Validation of MdmX as a therapeutic target for reactivating p53 in tumors AKT regulates NPM dependent ARF localization and p53mut stability in tumors.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2

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P2860

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

http://www.wikidata.org/entity/Q53334281

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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name

Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

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Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

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type

label

Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

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Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

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prefLabel

Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

@en

Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

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Nature Cell Biology

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Dose-dependent oncogene-induce ...... during mammary tumorigenesis.

@en

P2093

Blaine A Keister

http://www.w3.org/2001/XMLSchema#string

Christopher J Sarkisian

http://www.w3.org/2001/XMLSchema#string

Douglas B Stairs

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Lewis A Chodosh

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Robert B Boxer

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Susan E Moody

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P2860

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

RAS is regulated by the let-7 microRNA family

Creation of human tumour cells with defined genetic elements

Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

The activation of phosphatidylinositol 3-kinase by Ras

AP-1 in cell proliferation and survival

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493-505

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scholarly article

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10.1038/NCB1567

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5

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9

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2007-04-22T00:00:00Z

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6379056

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17450133

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