Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.
about
"Sentinel" circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary diseaseUpregulation of FOXM1 induces genomic instability in human epidermal keratinocytesProteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradationRequirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C MutationExtracellular Superoxide Dismutase: Growth Promoter or Tumor Suppressor?Oncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer CellsThe FHIT gene product: tumor suppressor and genome "caretaker"A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerCancer stem cells: the lessons from pre-cancerous stem cellsRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cellsPI3K pathway alterations in cancer: variations on a themeTransformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation processCell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cellsp21 in cancer: intricate networks and multiple activitiesFrequency-modulated pulses of ERK activity transmit quantitative proliferation signals.Suppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics.Cold-inducible RNA-binding protein bypasses replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activationLimited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.Minireview: physiological and pathological actions of RAS in the ovary.A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesisCopy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AMLTCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activationERBB2 increases metastatic potentials specifically in androgen-insensitive prostate cancer cells.The inflammatory network: bridging senescent stroma and epithelial tumorigenesis.Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestineTissue-specific p19Arf regulation dictates the response to oncogenic K-ras.Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistanceSelective activation of p53-mediated tumour suppression in high-grade tumours.Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.Validation of MdmX as a therapeutic target for reactivating p53 in tumorsAKT regulates NPM dependent ARF localization and p53mut stability in tumors.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2
P2860
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P2860
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@en
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@nl
type
label
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@en
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@nl
prefLabel
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@en
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@nl
P2093
P2860
P356
P1433
P1476
Dose-dependent oncogene-induce ...... during mammary tumorigenesis.
@en
P2093
Blaine A Keister
Christopher J Sarkisian
Douglas B Stairs
Lewis A Chodosh
Robert B Boxer
Susan E Moody
P2860
P2888
P304
P356
10.1038/NCB1567
P577
2007-04-22T00:00:00Z