Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes.
about
On the future of mass-spectrometry-based lipidomicsDefect of insulin signal in peripheral tissues: Important role of ceramideCeramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosisImaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient MiceReduced ceramide synthase 2 activity causes progressive myoclonic epilepsySphingolipid metabolites in inflammatory disease.Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubesHepatic fatty acid uptake is regulated by the sphingolipid acyl chain length.Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity.The Impact of Ischemia/Reperfusion Injury on Liver Allografts from Deceased after Cardiac Death versus Deceased after Brain Death Donors.Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via K(Ca) 1.1 upregulation.Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chainKCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stressProtection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalizationAltering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalizationRole of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in GlucosylceramideGM3 and diabetes.Sphingolipids and mitochondrial apoptosis.Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.Regulation of ceramide channel formation and disassembly: Insights on the initiation of apoptosis.Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.Compounds of the sphingomyelin-ceramide-glycosphingolipid pathways as secondary messenger molecules: new targets for novel therapies for fatty liver disease and insulin resistance.Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea.Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis.Dietary sphingolipids: potential for management of dyslipidemia and nonalcoholic fatty liver disease.Sphingolipids: membrane microdomains in brain development, function and neurological diseases.LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme.Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils.Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients.Development of pheochromocytoma in ceramide synthase 2 null mice.Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in hepatitis C virus but not hepatitis B virus infection.Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains.Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.Association of cultured myotubes and fasting plasma metabolite profiles with mitochondrial dysfunction in type 2 diabetes subjects.Increased Plasma Levels of Select Deoxy-ceramide and Ceramide Species are Associated with Increased Odds of Diabetic Neuropathy in Type 1 Diabetes: A Pilot Study.Decreased plasma levels of select very long chain ceramide species are associated with the development of nephropathy in type 1 diabetes.Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis.Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability.Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance.Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment.
P2860
Q27012927-CD1F645A-B0C9-46B4-9527-3D42936F4BC1Q27690875-318E3D04-1F0D-495B-92B2-5E4D85ADF2A2Q28547365-EE70434C-417A-4FCE-8A26-05836C6DD97EQ28550974-7DE906C9-45BA-431A-8664-76F9DA81DF1BQ34418788-DB7448D2-E2E8-42E8-88A1-AC2E5A17BA84Q35061720-4BAACA95-3043-46EE-B172-EFE72BB63A7BQ35078615-65B170C7-E348-48FB-A989-DB94D67BB4A7Q35522279-6ABD89F9-C623-4087-8BA1-1701EEA106E7Q35667288-00C473C7-1174-409D-876F-122110F84C88Q35919682-E0B37647-BAF6-4B07-9F95-5712B4F5E8C0Q36409978-F3568B51-13F4-43D9-B54B-FDA7D5F4001DQ36620822-D3CF940B-6426-4F20-B91B-0A73C61FA53DQ37235576-108F27B8-C946-4CFE-B251-94D28C8ADFF0Q37312126-4DD82F28-664D-4A18-8DDD-904D82BFCB2AQ37357098-F24794B6-0C6B-4098-99B5-EAA3B05F3241Q37377548-9A4F9D15-9727-43EC-9185-3C3D5B288B0FQ38176565-CB46F180-0665-4655-9EDA-06C5E954DCBFQ38332040-1FA3C440-44EE-48CF-9C0F-67AB0E8966A7Q38392764-7EEF76C4-C8CC-40A9-8C34-35B99A09C927Q38639669-A44197CF-EE93-490A-8118-BCD1FA208597Q38711466-2E36E7A6-C0C9-4397-819A-CB34CD646248Q38833111-2EB0AE8F-BB50-4AEF-B950-711BBD099F1AQ38880061-9869EB8A-161F-4F5B-A3D7-C9ABC5AEBF42Q38916409-C7BD65DC-841C-4538-A75A-16D497D40BD5Q39224276-1A0C7C74-9CC7-41E4-B05C-DAB697F7F96DQ39342245-3791ABCA-0621-4D53-8B00-BF1FB6EC232AQ40727621-13C5B42B-90DC-4853-8F88-2DB23C837BFBQ41126508-6C68BDC8-F2EC-489F-B896-F7EAFDAE566DQ41182983-ECC2010F-477D-41B0-8271-FDA1E7BED5DDQ41625711-6530B226-52B2-440E-8329-0162DD37C233Q41687237-F59777D2-230D-4D9E-8C7B-973F79B3A2F7Q42639375-4DB87E3D-35F4-482A-A447-FF725D974F20Q43895216-3290BEE1-0428-4F2C-AE25-19E37951F3AAQ46333323-DD4EE2F3-66AA-4086-8033-9989CA144CEBQ46521690-057A9C21-76E7-4390-8ED0-50641693FA98Q46856946-B5F877F4-5BEC-4181-A554-80DB709E19ECQ47132347-B56F776B-76AC-4F0C-AE67-A887A8D8EADCQ47157018-1913B2AD-3C7A-44C1-A607-7C63CE81B8DFQ47161992-83786730-ACFD-4399-A7D9-D6B5FA69A0EEQ47671597-153DFEC7-7C9D-403E-9F48-7BF57F126C16
P2860
Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Ablation of very long acyl cha ...... detergent-resistant membranes.
@en
Ablation of very long acyl cha ...... detergent-resistant membranes.
@nl
type
label
Ablation of very long acyl cha ...... detergent-resistant membranes.
@en
Ablation of very long acyl cha ...... detergent-resistant membranes.
@nl
prefLabel
Ablation of very long acyl cha ...... detergent-resistant membranes.
@en
Ablation of very long acyl cha ...... detergent-resistant membranes.
@nl
P2093
P2860
P356
P1433
P1476
Ablation of very long acyl cha ...... detergent-resistant membranes.
@en
P2093
Joo-Won Park
Sigalit Boura-Halfon
Woo-Jae Park
Yael Kuperman
Yael Pewzner-Jung
P2860
P304
P356
10.1002/HEP.26015
P407
P577
2012-12-06T00:00:00Z