Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
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Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesisProtein kinase C iota: human oncogene, prognostic marker and therapeutic targetAldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cellsRedox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and TherapyTargeting Protein Kinase C Downstream of Growth Factor and Adhesion SignallingRole of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia developmentProtein kinase C delta negatively modulates canonical Wnt pathway and cell proliferation in colon tumor cell linesHydrophobic protein in colorectal cancer in relation to tumor stages and gradesInducible nitric oxide synthase (iNOS) mediates the early increase of blood supply (EIBS) in colon carcinogenesis.Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanomaEfficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.Regulation of beta-catenin and connexin-43 expression: targets for sphingolipids in colon cancer prevention.Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colonA Gynecologic Oncology Group phase II trial of the protein kinase C-beta inhibitor, enzastaurin and evaluation of markers with potential predictive and prognostic value in persistent or recurrent epithelial ovarian and primary peritoneal malignancieCyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.Aberrant crypt foci as microscopic precursors of colorectal cancer.Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl).Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemopreventionC1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosisWealth of opportunity - the C1 domain as a target for drug development.Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.Protein kinase C betaII and TGFbetaRII in omega-3 fatty acid-mediated inhibition of colon carcinogenesis.Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.Characterisation and protein expression profiling of annexins in colorectal cancer.Protein kinase C isozymes as therapeutic targets for treatment of human cancers.Protein kinase C beta in malignant pleural mesotheliomaA pharmacokinetic and safety study of a fixed oral dose of enzastaurin HCl in native Chinese patients with refractory solid tumors and lymphoma.Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survivalProtein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progressionPKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formationProtein kinase Cbeta is an effective target for chemoprevention of colon cancer.The multifaceted effects of omega-3 polyunsaturated Fatty acids on the hallmarks of cancer.PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cellsGenetically encoded fluorescent reporters to visualize protein kinase C activation in live cells.Enzastaurin inhibits invasion and metastasis in lung cancer by diverse molecules.Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation.Protein kinase C: an attractive target for cancer therapy.
P2860
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P2860
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@en
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@nl
type
label
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@en
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@nl
prefLabel
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@en
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@nl
P2093
P1433
P1476
Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.
@en
P2093
Gatalica Z
Gökmen-Polar Y
Velasco MA
P304
P407
P577
2001-02-01T00:00:00Z