Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
about
Protein kinase C iota: human oncogene, prognostic marker and therapeutic targetChemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζmTOR signaling in tumorigenesisAsymmetric cell division of stem and progenitor cells during homeostasis and cancerProtein kinase C iota regulates pancreatic acinar-to-ductal metaplasiaPKC eta as a therapeutic target in glioblastoma multiforme.The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasisProtein kinase Cι expression and oncogenic signaling mechanisms in cancer.Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iotaProtein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanismProtein kinase C iota in the intestinal epithelium protects against dextran sodium sulfate-induced colitis.Expression of polarity genes in human cancer.Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinoma.NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loopProtein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.The biology and biochemistry of diacylglycerol signalling. Meeting on molecular advances in diacylglycerol signalling.Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery?PKCι counteracts oxidative stress by regulating Hsc70 in an esophageal cancer cell line.PKCiota promotes ovarian tumor progression through deregulation of cyclin E.Genome-wide association study of colorectal cancer in Hispanics.p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression.Protein kinase C isozymes as therapeutic targets for treatment of human cancers.Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells.Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progressionInhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.Par complex in cancer: a regulator of normal cell polarity joins the dark side.Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA.aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.PKCι maintains a tumor-initiating cell phenotype that is required for ovarian tumorigenesis.Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice.Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex.Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer.Targeting oncogenic protein kinase Cι for treatment of mutant KRAS LADC.The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma.Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment.
P2860
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P2860
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@ast
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@en
type
label
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@ast
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@en
prefLabel
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@ast
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@en
P2093
P2860
P356
P1476
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo.
@en
P2093
Alan P Fields
Deborah Sier
E Aubrey Thompson
Lee Jamieson
Nicole R Murray
Panos Anastasiadis
Wangsheng Yu
Yesim Gökmen-Polar
Zoran Gatalica
P2860
P304
P356
10.1083/JCB.200311011
P407
P577
2004-03-01T00:00:00Z