Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria. - Wikidata - awgldk - TriplyDB

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

http://www.wikidata.org/entity/Q53635685

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Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis Target identification by image analysis Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides Pretubulysin: a new option for the treatment of metastatic cancer.Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.NMR in natural products: understanding conformation, configuration and receptor interactions.Tubulin inhibitors: a patent review.Chemistry and biology of tubulysins: antimitotic tetrapeptides with activity against drug resistant cancers.Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy.The tubulysin analogue KEMTUB10 induces apoptosis in breast cancer cells via p53, Bim and Bcl-2.Total synthesis of tubulysin U and its C-4 epimer.Synthesis and structure-activity relationship studies of novel tubulysin U analogues--effect on cytotoxicity of structural variations in the tubuvaline fragment.Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.Establishing a High-content Analysis Method for Tubulin Polymerization to Evaluate Both the Stabilizing and Destabilizing Activities of Compounds.Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog.Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2.KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation.Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A.The pretubulysin-induced exposure of collagen is caused by endothelial cell retraction that results in an increased adhesion and decreased transmigration of tumor cells.Stabilizing a Tubulysin Antibody-Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors.Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads.

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P2860

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

http://www.wikidata.org/entity/Q53635685

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

@wuu

2006年学术文章

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2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

2006年學術文章

@zh

2006年學術文章

@zh-hant

name

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@en

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@nl

type

label

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@en

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@nl

prefLabel

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@en

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@nl

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P1476

Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

@en

P2093

Florenz Sasse

http://www.w3.org/2001/XMLSchema#string

Hans Reichenbach

http://www.w3.org/2001/XMLSchema#string

Mohamed W Khalil

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Yasser A Elnakady

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P2860

HIV-1 rev depolymerizes microtubules to form stable bilayered rings

The cryptophycin-tubulin ring structure indicates two points of curvature in the tubulin dimer

Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity.

Antimitotic natural products and their interactions with tubulin.

Interactions of antimitotic peptides and depsipeptides with tubulin.

Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B.

Interactions of the catharanthus (Vinca) alkaloids with tubulin and microtubules.

Isolation of dolastatin 10 from the marine cyanobacterium Symploca species VP642 and total stereochemistry and biological evaluation of its analogue symplostatin 1.

Myxobacterial epothilones and tubulysins as promising anticancer agents.

Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells.

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678-683

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scholarly article

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10.1002/CBIC.200500421

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4

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7

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Heinrich Lünsdorf

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2006-04-01T00:00:00Z

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16491500

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