Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics.
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Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channelsMolecular dissection of functional domains of the E1E2-ATPase using sodium and calcium pump chimeric molecules.Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels.Functional expression of transgenic 1sDHPR channels in adult mammalian skeletal muscle fibres.The S5-S6 linker of repeat I is a critical determinant of L-type Ca2+ channel conductanceRole of S4 segments and the leucine heptad motif in the activation of an L-type calcium channelCa2+ current activation rate correlates with alpha 1 subunit density.Charge movement and SR calcium release in frog skeletal muscle can be related by a Hodgkin-Huxley model with four gating particles.Molecular analysis of voltage dependence of heterotypic gap junctions formed by connexins 26 and 32Molecular origin of the L-type Ca2+ current of skeletal muscle myotubes selectively deficient in dihydropyridine receptor beta1a subunitDifferential regulation of skeletal muscle L-type Ca2+ current and excitation-contraction coupling by the dihydropyridine receptor beta subunit.Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscleThe structure of Ca(2+) release units in arthropod body muscle indicates an indirect mechanism for excitation-contraction couplingControl of ion conduction in L-type Ca2+ channels by the concerted action of S5-6 regions.Malignant hyperthermia and excitation-contraction coupling.Multiple loops of the dihydropyridine receptor pore subunit are required for full-scale excitation-contraction coupling in skeletal muscle.Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscleApparent lack of physical or functional interaction between CaV1.1 and its distal C terminus.Pore stability and gating in voltage-activated calcium channelsDomain III regulates N-type (CaV2.2) calcium channel closing kineticsFormation of triads without the dihydropyridine receptor alpha subunits in cell lines from dysgenic skeletal muscleShaker potassium channel gating. III: Evaluation of kinetic models for activation.Single calcium channel behavior in native skeletal muscle.Role of the S4 in cooperativity of voltage-dependent potassium channel activation.Isolation of myocardial L-type calcium channel gating currents with the spider toxin omega-Aga-IIIA.Unitary behavior of skeletal, cardiac, and chimeric L-type Ca2+ channels expressed in dysgenic myotubes.Bay K 8644 reveals two components of L-type Ca2+ channel current in clonal rat pituitary cellsL-type Ca2+ channels access multiple open states to produce two components of Bay K 8644-dependent current in GH3 cells.Role of calcium permeation in dihydropyridine receptor function. Insights into channel gating and excitation-contraction coupling.Functional impact of the ryanodine receptor on the skeletal muscle L-type Ca(2+) channelPotentiation of the cardiac L-type Ca(2+) channel (alpha(1C)) by dihydropyridine agonist and strong depolarization occur via distinct mechanisms.Impaired gating of an L-Type Ca(2+) channel carrying a mutation linked to malignant hyperthermia.Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channelsReciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation.L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder.Application of patch clamp methods to the study of calcium currents and calcium channelsStructure and function of voltage-dependent calcium channels from muscle.Stable and functional expression of the calcium channel alpha 1 subunit from smooth muscle in somatic cell lines.
P2860
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P2860
Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@en
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@nl
type
label
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@en
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@nl
prefLabel
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@en
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@nl
P2093
P356
P1433
P1476
Repeat I of the dihydropyridin ...... m channel activation kinetics.
@en
P2093
P2888
P304
P356
10.1038/352800A0
P407
P577
1991-08-01T00:00:00Z
P5875
P6179
1005841189