TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. - Wikidata - awgldk - TriplyDB

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

http://www.wikidata.org/entity/Q54283283

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TRPM4 channels in smooth muscle function Re-evaluating the treatment of acute optic neuritis.Progressive multiple sclerosis: from pathogenic mechanisms to treatment.Transient receptor potential (TRP) channels: a clinical perspective Taste dysfunction in multiple sclerosis Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death.9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury Complex I subunit gene therapy with NDUFA6 ameliorates neurodegeneration in EAE Physiological functions of the TRPM4 channels via protein interactions Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis.TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function.The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide.Activity of NaV1.2 promotes neurodegeneration in an animal model of multiple sclerosis.Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy.Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects.Discovery of novel disease-specific and membrane-associated candidate markers in a mouse model of multiple sclerosis.Malignant infarction of the middle cerebral artery in a porcine model. A pilot study.The TRPM4 channel inhibitor 9-phenanthrol.Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis.Dysfunction of neuronal calcium signalling in neuroinflammation and neurodegeneration.Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis.Transient Receptor Potential (TRP) channels in T cells.What is the evidence for the role of TRP channels in inflammatory and immune cells?Neurodegeneration in multiple sclerosis and neuromyelitis optica.Nogo-A Antibodies for Progressive Multiple Sclerosis.Targeting ion channels for the treatment of autoimmune neuroinflammation.Plasticity of Th17 Cells in Autoimmune Kidney Diseases.Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor.Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity.Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122.Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy.TRPM4 inhibition promotes angiogenesis after ischemic stroke.Ca2+ and calpain mediate capsaicin-induced ablation of axonal terminals expressing transient receptor potential vanilloid 1.Regulation and dysregulation of axon infrastructure by myelinating glia.Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels.Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation.

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TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

http://www.wikidata.org/entity/Q54283283

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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type

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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TRPM4 cation channel mediates ...... elitis and multiple sclerosis.

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Aurélie Menigoz

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Benjamin Schattling

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Doron Merkler

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Edda Thies

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Friederike Ufer

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Karin Steinbach

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Marc Freichel

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Martin Kruse

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Matthias Kneussel

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Olaf Pongs

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P2860

Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I

Cloning and characterization of rat transient receptor potential-melastatin 4 (TRPM4)

Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells.

A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases

Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis

TRPM4 regulates calcium oscillations after T cell activation

Multiple sclerosis

Identification and characterization of the murine TRPM4 channel

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1805-1811

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10.1038/NM.3015

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12

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18

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Manuel A. Friese

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2012-11-18T00:00:00Z

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233537573

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23160238

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experimental autoimmune encephalomyelitis

multiple sclerosis