BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic β-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2.
about
Regulation of Bim in Health and DiseaseLong noncoding RNA variations in cardiometabolic diseases.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cellsShared Genetic Basis for Type 1 Diabetes, Islet Autoantibodies, and Autoantibodies Associated With Other Immune-Mediated Diseases in Families With Type 1 DiabetesER stress and the decline and fall of pancreatic beta cells in type 1 diabetes.Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta CellsmicroRNA-142 is upregulated by tumor necrosis factor-alpha and triggers apoptosis in human gingival epithelial cells by repressing BACH2 expressionViral infections in type 1 diabetes mellitus--why the β cells?How apoptotic β-cells direct immune response to tolerance or to autoimmune diabetes: a review.Genes affecting β-cell function in type 1 diabetes.Persistent coxsackievirus B4 infection induces microRNA dysregulation in human pancreatic cells.Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis.Mass production of functional human pancreatic β-cells: why and how?Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis.Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.Association investigation of BACH2 rs3757247 and SOD2 rs4880 polymorphisms with the type 1 diabetes and diabetes long-term complications risk in the Polish population.Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway.Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).Type 1 diabetes genome-wide association studies: not to be lost in translation.Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes.Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis.Pancreatic Beta Cell Survival and Signaling Pathways: Effects of Type 1 Diabetes-Associated Genetic Variants.The Role of BACH2 in T Cells in Experimental Malaria Caused by AS
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P2860
BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic β-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2.
description
2014 nî lūn-bûn
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name
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@en
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@nl
type
label
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@en
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@nl
prefLabel
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@en
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@nl
P50
P356
P1433
P1476
BACH2, a candidate risk gene f ...... with the candidate gene PTPN2.
@en
P2093
Decio L Eizirik
P304
P356
10.2337/DB13-1443
P407
P577
2014-03-07T00:00:00Z