Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase.
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Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanismStructural Insights into the Recovery of Aldolase Activity inN-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis StrategyStructure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus PolymerisationCrystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitorThe catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases.Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configurationThe importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases.Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.Chemical modification of Saccharomycopsis fibuligera R64 α-amylase to improve its stability against thermal, chelator, and proteolytic inactivation.FtsH-dependent processing of RNase colicins D and E3 means that only the cytotoxic domains are imported into the cytoplasm.Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired foldMembrane proteases in the bacterial protein secretion and quality control pathway.The Acinetobacter regulatory UmuDAb protein cleaves in response to DNA damage with chimeric LexA/UmuD characteristics.Fluorescence spectroscopy of soluble E. coli SPase I Δ2-75 reveals conformational changes in response to ligand binding.Signal peptidase I: cleaving the way to mature proteins.Chemical mutagenesis of vaccinia DNA topoisomerase lysine 167 provides insights to the catalysis of DNA transesterification.A classical and ab initio study of the interaction of the myosin triphosphate binding domain with ATP.The Stable Interaction Between Signal Peptidase LepB of Escherichia coli and Nuclease Bacteriocins Promotes Toxin Entry into the Cytoplasm.Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidasesCloning, expression, and purification of functional Sec11a and Sec11b, type I signal peptidases of the archaeon Haloferax volcanii.Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism.Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor.Identification of arginine residues important for the activity of Escherichia coli signal peptidase I.Plastidic type I signal peptidase 1 is a redox-dependent thylakoidal processing peptidase.Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites.The Sec System: Protein Export in Escherichia coli.The role of the conserved box E residues in the active site of the Escherichia coli type I signal peptidase.The low barrier hydrogen bond in enzymatic catalysis.
P2860
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P2860
Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Use of site-directed chemical ...... erichia coli leader peptidase.
@en
Use of site-directed chemical ...... erichia coli leader peptidase.
@nl
type
label
Use of site-directed chemical ...... erichia coli leader peptidase.
@en
Use of site-directed chemical ...... erichia coli leader peptidase.
@nl
prefLabel
Use of site-directed chemical ...... erichia coli leader peptidase.
@en
Use of site-directed chemical ...... erichia coli leader peptidase.
@nl
P2093
P2860
P356
P1476
Use of site-directed chemical ...... erichia coli leader peptidase.
@en
P2093
Bullinger PR
Casareno R
Strynadka NC
Tschantz WR
P2860
P304
9994-10003
P356
10.1074/JBC.272.15.9994
P407
P577
1997-04-01T00:00:00Z