Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
about
Output-mode transitions are controlled by prolonged inactivation of sodium channels in pyramidal neurons of subiculum.Functional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humansThe Hodgkin-Huxley heritage: from channels to circuitsCrystal structure of a voltage-gated sodium channel in two potentially inactivated statesDeciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestorsChannelopathies of skeletal muscle excitabilitySlow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunitResidue-specific effects on slow inactivation at V787 in D2-S6 of Na(v)1.4 sodium channels.A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivationStructure and function of voltage-gated sodium channels at atomic resolution.Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibuleA mutation in segment I-S6 alters slow inactivation of sodium channels.Slow inactivation differs among mutant Na channels associated with myotonia and periodic paralysis.Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels.Gating of cardiac Na+ channels in excised membrane patches after modification by alpha-chymotrypsin.Fast and slow inactivation of sodium channels: effects of photodynamic modification by methylene blueSlow and incomplete inactivations of voltage-gated channels dominate encoding in synthetic neurons.Impaired slow inactivation in mutant sodium channelsInteraction between fast and slow inactivation in Skm1 sodium channelsIn silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating sodium channel slow inactivationSteady-state availability of sodium channels. Interactions between activation and slow inactivation.Slow inactivation in human cardiac sodium channelsCharge immobilization caused by modification of internal cysteines in squid Na channelsProperties of slow, cumulative sodium channel inactivation in rat hippocampal CA1 pyramidal neurons.Enhanced slow inactivation by V445M: a sodium channel mutation associated with myotoniaStructural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels.Voltage-dependent sodium channel function is regulated through membrane mechanics.Isoform-specific lidocaine block of sodium channels explained by differences in gatingTryptophan scanning of D1S6 and D4S6 C-termini in voltage-gated sodium channelsTryptophan substitution of a putative D4S6 gating hinge alters slow inactivation in cardiac sodium channels.Removal of sodium inactivation and block of sodium channels by chloramine-T in crayfish and squid giant axonsModification of K channel inactivation by papain and N-bromoacetamideNa channel activation gate modulates slow recovery from use-dependent block by local anesthetics in squid giant axonsStatistical analysis of single sodium channels. Effects of N-bromoacetamideMolecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb.Kinetic model of Nav1.5 channel provides a subtle insight into slow inactivation associated excitability in cardiac cells.Functional properties and differential neuromodulation of Na(v)1.6 channels.Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium channels.Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones.Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain.
P2860
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P2860
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年学术文章
@wuu
1978年学术文章
@zh-cn
1978年学术文章
@zh-hans
1978年学术文章
@zh-my
1978年学术文章
@zh-sg
1978年學術文章
@yue
1978年學術文章
@zh
1978年學術文章
@zh-hant
name
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@en
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@nl
type
label
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@en
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@nl
prefLabel
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@en
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@nl
P1476
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.
@en
P356
10.1113/JPHYSIOL.1978.SP012485
P407
P577
1978-10-01T00:00:00Z