A vector for expressing foreign genes in the brains and hearts of transgenic mice - Wikidata - awgldk - TriplyDB

A vector for expressing foreign genes in the brains and hearts of transgenic mice

A vector for expressing foreign genes in the brains and hearts of transgenic mice

http://www.wikidata.org/entity/Q54965153

about

Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation.Mouse models of polyglutamine diseases: review and data table. Part I Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.Transgenic Mouse Bioassay: Evidence That Rabbits Are Susceptible to a Variety of Prion Isolates Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein Endoproteolytic processing and stabilization of wild-type and mutant presenilin Structural effects of PrP polymorphisms on intra- and interspecies prion transmission.SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43.Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases.The N-terminal, polybasic region is critical for prion protein neuroprotective activity.Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9.Development of a novel cellular model of Alzheimer's disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain Animal models of amyloid-beta-related pathologies in Alzheimer's disease.Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.Versatile somatic gene transfer for modeling neurodegenerative diseases.The FAM3 superfamily member ILEI ameliorates Alzheimer's disease-like pathology by destabilizing the penultimate amyloid-β precursor.DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G)E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation.Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis The roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease.Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.A naturally occurring C-terminal fragment of the prion protein (PrP) delays disease and acts as a dominant-negative inhibitor of PrPSc formation.Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.MicroRNAs 99b-5p/100-5p Regulated by Endoplasmic Reticulum Stress are Involved in Abeta-Induced Pathologies.BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo Characterization of conformation-dependent prion protein epitopes.Cellular prion protein: from physiology to pathology.Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models.

P2860

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P2860

A vector for expressing foreign genes in the brains and hearts of transgenic mice

http://www.wikidata.org/entity/Q54965153

description

1996 nî lūn-bûn

@nan

1996年の論文

@ja

1996年学术文章

@wuu

1996年学术文章

@zh

1996年学术文章

@zh-cn

1996年学术文章

@zh-hans

1996年学术文章

@zh-my

1996年学术文章

@zh-sg

1996年學術文章

@yue

1996年學術文章

@zh-hant

name

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@en

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@nl

type

label

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@en

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@nl

prefLabel

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@en

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@nl

P1433

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Q54965153-B57C44E0-57E6-48AE-989B-1819F0E768A4

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Q54965153-2D011468-43D4-491B-8BE6-3ABD237CC273

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P577

Q54965153-F62CF931-DBED-4B96-A0AF-43247F36E82C

P356

S1050-3862(96)00167-2

P1433

Genetic analysis, techniques and applications

P1476

A vector for expressing foreign genes in the brains and hearts of transgenic mice

@en

P2093

David R. Borchelt

http://www.w3.org/2001/XMLSchema#string

Donald L. Price

http://www.w3.org/2001/XMLSchema#string

Hilda H. Slunt

http://www.w3.org/2001/XMLSchema#string

Janine Davis

http://www.w3.org/2001/XMLSchema#string

Jean Regard

http://www.w3.org/2001/XMLSchema#string

Marek Fischer

http://www.w3.org/2001/XMLSchema#string

Micheal K. Lee

http://www.w3.org/2001/XMLSchema#string

Sangram S. Sisodia

http://www.w3.org/2001/XMLSchema#string

Tamara Ratovitsky

http://www.w3.org/2001/XMLSchema#string

P304

159-163

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P31

scholarly article

P356

10.1016/S1050-3862(96)00167-2

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P433

6

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P478

13

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P50

Neal G. Copeland

Nancy A. Jenkins

P577

1996-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime