Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.
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Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.Multifactorial analysis of predictors of outcome in pediatric intracranial ependymomaTelomere maintenance and dysfunction predict recurrence in paediatric ependymomaReactivation of telomerase in cancerAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionToward a molecular classification of colorectal cancer: the role of telomere lengthThe Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeGenetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma CellsPML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cellsAssessing telomeric DNA content in pediatric cancers using whole-genome sequencing data.TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entitiesIncreased paired box transcription factor 8 has a survival function in gliomaPrognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis.Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres.Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.Twisted epithelial-to-mesenchymal transition promotes progression of surviving bladder cancer T24 cells with hTERT-dysfunction.Altered telomeres in tumors with ATRX and DAXX mutations.Multiple Mechanisms Contribute To Telomere Maintenance.Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres.Telomere maintenance mechanisms in cancer: clinical implicationsTelomere profiling: toward glioblastoma personalized medicine.Telomeric recombination induced by dysfunctional telomeres.Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer.Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramaticallyPrevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.Organ aging and susceptibility to cancer may be related to the geometry of the stem cell niche.Expression of various protection of telomeres 1 variants is associated with telomere length and radiosensitivity in colon and gastric adenocarcinoma cells in vitro.Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade.Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengthsTelomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevancePrognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosisSelective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant gliomaFrequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.p53 and disease: when the guardian angel fails.
P2860
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P2860
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Alternative lengthening of tel ...... with glioblastoma multiforme.
@en
Alternative lengthening of tel ...... with glioblastoma multiforme.
@nl
type
label
Alternative lengthening of tel ...... with glioblastoma multiforme.
@en
Alternative lengthening of tel ...... with glioblastoma multiforme.
@nl
prefLabel
Alternative lengthening of tel ...... with glioblastoma multiforme.
@en
Alternative lengthening of tel ...... with glioblastoma multiforme.
@nl
P2093
P1433
P1476
Alternative lengthening of tel ...... s with glioblastoma multiforme
@en
P2093
D A Jellinek
V Hakin-Smith
W R Timperley
P304
P356
10.1016/S0140-6736(03)12681-5
P407
P577
2003-03-01T00:00:00Z