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Phosphopeptide selective coordination complexes as promising SRC homology 2 domain mimetics.Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.Mapping the cellular response to small molecules using chemogenomic fitness signatures.Glucopsychosine increases cytosolic calcium to induce calpain-mediated apoptosis of acute myeloid leukemia cells.Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26.New sources of drugs for hematologic malignanciesFood as a drug.Synthesis and evaluation of alendronate-modified gelatin biopolymer as a novel osteotropic nanocarrier for gene therapy.Mitochondrial DNA damage by bleomycin induces AML cell death.Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity.A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.DNA ministrings: highly safe and effective gene delivery vectors.A potential bioactive hard-stock fat replacer comprised of a molecular gel.The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma.Lactoferrin effect on lymphocyte cytokines and apoptosis is independent of exercise.Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death.Diosmetin Induces Apoptosis of Acute Myeloid Leukemia Cells.Dietary lactoferrin does not prevent dextran sulfate sodium induced murine intestinal lymphocyte death.Effect of short-term dietary intake of bovine lactoferrin on intestinal lymphocyte apoptosis in healthy mice.Repeated exercise in mice alters expression of IL-10 and TNF-alpha in intestinal lymphocytes.Analytical Method To Detect and Quantify Avocatin B in Hass Avocado Seed and Pulp Matter.Freewheel exercise training modifies pro- and anti-apoptotic protein expression in mouse splenic lymphocytesEffect of repeated exercise stress on caspase 3, Bcl-2, HSP 70 and CuZn-SOD protein expression in mouse intestinal lymphocytesThe mitochondria target drug avocatin B synergizes with induction chemotherapeutics to induce leukemia cell deathAvocatin B Protects Against Lipotoxicity and Improves Insulin Sensitivity in Diet-Induced Obesity
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description
researcher
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wetenschapper
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հետազոտող
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name
Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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Paul A. Spagnuolo
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P106
P1153
36864976300
P21
P31
P496
0000-0002-2431-4368