Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis - Wikidata - awgldk - TriplyDB

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

http://www.wikidata.org/entity/Q56914273

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CD8(+) T-Cells as Immune Regulators of Multiple Sclerosis Involvement of CD8(+) T Cells in Multiple Sclerosis Novel Insights and Therapeutics in Multiple Sclerosis Role of T cell-glial cell interactions in creating and amplifying central nervous system inflammation and multiple sclerosis disease symptoms Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases Models of autoimmune demyelination in the central nervous system: on the way to translational medicine.Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells.Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population.Autoimmune T cell responses in the central nervous system HLA-class I markers and multiple sclerosis susceptibility in the Italian population Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy.Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs.Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function.Spontaneous ocular and neurologic deficits in transgenic mouse models of multiple sclerosis and noninvasive investigative modalities: a review DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele Constitutively active Lck kinase in T cells drives antigen receptor signal transduction T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy Immune tolerance in multiple sclerosis.Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct.Experimental Autoimmune Encephalomyelitis in Mice A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells.Genetic determinants of risk and progression in multiple sclerosis.Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.An integrated approach to design novel therapeutic interventions for demyelinating disorders Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions Progress in multiple sclerosis genetics.Glatiramer acetate in treatment of multiple sclerosis: a toolbox of random co-polymers for targeting inflammatory mechanisms of both the innate and adaptive immune system?MHC class I-restricted myelin epitopes are cross-presented by Tip-DCs that promote determinant spreading to CD8⁺ T cells.Antidiabetogenic MHC class II promotes the differentiation of MHC-promiscuous autoreactive T cells into FOXP3+ regulatory T cells.Modeling the heterogeneity of multiple sclerosis in animals Natural killer cells and their receptors in multiple sclerosis.Immunology and oxidative stress in multiple sclerosis: clinical and basic approach.Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies.CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?

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Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

http://www.wikidata.org/entity/Q56914273

description

article

@en

im Oktober 2008 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в жовтні 2008

@uk

name

Opposing effects of HLA class ...... T cells in multiple sclerosis

@en

Opposing effects of HLA class ...... T cells in multiple sclerosis

@nl

type

label

Opposing effects of HLA class ...... T cells in multiple sclerosis

@en

Opposing effects of HLA class ...... T cells in multiple sclerosis

@nl

prefLabel

Opposing effects of HLA class ...... T cells in multiple sclerosis

@en

Opposing effects of HLA class ...... T cells in multiple sclerosis

@nl

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P1433

Nature Medicine

P1476

Opposing effects of HLA class ...... T cells in multiple sclerosis

@en

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John I Bell

http://www.w3.org/2001/XMLSchema#string

Karen B Jakobsen

http://www.w3.org/2001/XMLSchema#string

Lars Fugger

http://www.w3.org/2001/XMLSchema#string

Lise T Jensen

http://www.w3.org/2001/XMLSchema#string

Lone Friis

http://www.w3.org/2001/XMLSchema#string

Matthew J Craner

http://www.w3.org/2001/XMLSchema#string

Ruth Etzensperger

http://www.w3.org/2001/XMLSchema#string

Véronique Huygelen

http://www.w3.org/2001/XMLSchema#string

P2860

Regulatory functions of CD8+CD28- T cells in an autoimmune disease model

Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.

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1227-1235

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scholarly article

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10.1038/NM.1881

http://www.w3.org/2001/XMLSchema#string

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P433

11

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14

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Manuel A. Friese

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2008-10-26T00:00:00Z

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18953350

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multiple sclerosis