about
Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferationBCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesisGeneration of bivalent chromatin domains during cell fate decisionsCytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors.Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges.FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.Delineating the mixed lineage leukemia gene expression network in hematopoietic stem cells.Delineating the cellular pathways of hematopoietic lineage commitment.Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitorsHematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitorsBcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype.Mapping cellular hierarchy by single-cell analysis of the cell surface repertoireThe earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.Strict in vivo specificity of the Bcl11a erythroid enhancer.Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis.Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.Dicer is selectively important for the earliest stages of erythroid development.FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Sidinh Luc
@ast
Sidinh Luc
@en
Sidinh Luc
@es
Sidinh Luc
@nl
type
label
Sidinh Luc
@ast
Sidinh Luc
@en
Sidinh Luc
@es
Sidinh Luc
@nl
prefLabel
Sidinh Luc
@ast
Sidinh Luc
@en
Sidinh Luc
@es
Sidinh Luc
@nl
P106
P31
P496
0000-0001-7006-6169