The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
about
A Tale from TGF-β Superfamily for Thymus Ontogeny and FunctionExtramedullary Manifestations of Myeloid NeoplasmsThymic B Cells and Central T Cell ToleranceUsing mouse models to study function of transcriptional factors in T cell developmentMulticongenic fate mapping quantification of dynamics of thymus colonization.An organized and functional thymus generated from FOXN1-reprogrammed fibroblastsTranscriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment.Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages.Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapyT cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.Human lymphoid development in the absence of common γ-chain receptor signaling.The Cytokine Flt3-Ligand in Normal and Malignant HematopoiesisNiche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.Hematopoietic progenitor cell lines with myeloid and lymphoid potentialA simple model system enabling human CD34(+) cells to undertake differentiation towards T cellsGrowth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.Early T-cell progenitors are the major granulocyte precursors in the adult mouse thymus.Intrathymic progenitor cell transplantation across histocompatibility barriers results in the persistence of early thymic progenitors and T-cell differentiation.In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis.Early events in lymphopoiesis: an update.FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitmentDistinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitorsConcise review: hematopoietic stem cell transplantation: targeting the thymus.Transcriptional control of early T and B cell developmental choicesThe chromatin landscape and transcription factors in T cell programming.Developmental gene networks: a triathlon on the course to T cell identity.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Hematopoietic stem cells: concepts, definitions, and the new reality.Hematopoiesis and T-cell specification as a model developmental system.MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment.Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus.miRNAs in Normal and Malignant Hematopoiesis.Cytokines, Transcription Factors, and the Initiation of T-Cell Development.The Human Thymus Is Enriched for Autoreactive B Cells.The transcriptional landscape of αβ T cell differentiation.Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in miceCharacterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis
P2860
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P2860
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@en
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@nl
type
label
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@en
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@nl
prefLabel
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@en
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@nl
P2093
P2860
P50
P356
P1433
P1476
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
@en
P2093
Alejandra Sanjuan-Pla
Alison Farley
Aniela Domanski
Claus Nerlov
Deborah Atkinson
Hanane Boukarabila
Helen Ferry
John Brown
Kristina Anderson
Marella de Bruijn
P2860
P304
P356
10.1038/NI.2255
P407
P50
P577
2012-02-19T00:00:00Z