Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells
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Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell linesIntravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cellsCell cycle gene networks are associated with melanoma prognosisMechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cellsBRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cellsGLI2-mediated melanoma invasion and metastasis.Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination.Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf.Microenvironment-derived factors driving metastatic plasticity in melanoma.A gene expression signature of invasive potential in metastatic melanoma cells[6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway.A role for ATF2 in regulating MITF and melanoma development.NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.Silencing of GPNMB by siRNA inhibits the formation of melanosomes in melanocytes in a MITF-independent fashionEfficient gene expression profiling of laser-microdissected melanoma metastases.Chromatin barcodes as biomarkers for melanoma.Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in miceMITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.MITF in melanoma: mechanisms behind its expression and activity.Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanomaMITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell linesMicroarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1rVariable Expression of GLIPR1 Correlates with Invasive Potential in Melanoma CellsRole of EZH2 histone methyltrasferase in melanoma progression and metastasisThe neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.In the Wnt-er of life: Wnt signalling in melanoma and ageing.Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.Advances in melanoma senescence and potential clinical application.Receptor tyrosine kinases and their activation in melanoma.MITF, the Janus transcription factor of melanoma.Cellular and molecular mechanisms controlling the migration of melanocytes and melanoma cells.Molecular networks in melanoma invasion and metastasis.Octamer-binding transcription factors: genomics and functions.MITF and PAX3 Play Distinct Roles in Melanoma Cell Migration; Outline of a "Genetic Switch" Theory Involving MITF and PAX3 in Proliferative and Invasive Phenotypes of Melanoma.The roles of microphthalmia-associated transcription factor and pigmentation in melanoma.Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy.Microphthalmia-associated transcription factor expression levels in melanoma cells contribute to cell invasion and proliferation.NFATc2 is an intrinsic regulator of melanoma dedifferentiation.Contemporary and potential future molecular diagnosis of melanoma.
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Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells
description
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 October 2008
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 2008
@uk
name
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@en
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@nl
type
label
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@en
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@nl
prefLabel
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@en
Brn-2 Represses Microphthalmia ...... Factor-Negative Melanoma Cells
@nl
P2093
P50
P1433
P1476
Brn-2 represses microphthalmia ...... factor-negative melanoma cells
@en
P2093
Dominique Kobi
Jane Goodall
Laurence Denat
Lionel Larue
P304
P356
10.1158/0008-5472.CAN-08-1053
P407
P577
2008-10-01T00:00:00Z