Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
about
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 functionPhosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.PIK3CA as an oncogene in cervical cancerTC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathwayCyclins: roles in mitogenic signaling and oncogenic transformationInterleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cellsAntisense and dominant-negative AKT2 cDNA inhibits glioma cell invasionDevelopment of a Whole Organism Platform for Phenotype-Based Analysis of IGF1R-PI3K-Akt-Tor Action.Computational identification of significant missense mutations in AKT1 gene.Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesisMechanisms of apoptosis by c-Myc.The role of c-myc in cellular growth control.Signal transduction pathways that regulate eukaryotic protein synthesis.Ethanol Extract of Alismatis rhizome Inhibits Adipocyte Differentiation of OP9 Cells.Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus.Paradigms of growth control: relation to Cdk activation.Phosphatidylinositol 3-kinases in tumor progression.Expression profile and molecular genetic regulation of cyclin D1 expression in epithelioid sarcoma.HSP90 as a new therapeutic target for cancer therapy: the story unfolds.Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein kinase 1/2 activation and deregulates gene expression in leukemia cells.Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma.MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma.Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibitionActivity of the heat shock protein 90 inhibitor ganetespib in melanomaRas family genes: an interesting link between cell cycle and cancer.Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle.L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways.Small-molecule cyclin-dependent kinase modulators.Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.The role of translation in neoplastic transformation from a pathologist's point of view.Postgenomic global analysis of translational control induced by oncogenic signaling.Translational control in T lymphocytes.Inhibitors of the mammalian target of rapamycin.Viruses - seeking and destroying the tumor program.Heat-shock protein 90 inhibitors in cancer therapy: 17AAG and beyond.Molecular biology of human gliomas.
P2860
Q24304442-8574D48C-EB99-42F6-8EE8-B6DAA8F18E82Q24801684-52FB6500-85B0-41F3-A315-C5C15CC48D33Q24810517-ED19DCAB-7809-45A6-86F9-2212BEEC079FQ27824772-C16FF7EE-936B-4D39-A234-32997EBA8DBFQ28138126-731D018B-916D-40B8-A0E3-4DE50BF38EA4Q28202079-37B3946C-D03B-4314-B8EE-53AB0782EDA8Q28289852-DE5367DF-29FE-4F86-96E3-8EC023837A04Q28295106-B742C23B-68F6-405D-8C6B-BD7A4BA7BB0FQ28569152-4408DD20-3882-4C05-9BD6-9205F6F11D54Q30356087-86AA8F29-CBBC-44AC-8ABE-82A6B857D141Q30362350-7D67E985-70A7-4C71-B769-E05D2C861EDFQ33539986-596FEAC1-921B-47BA-BF46-D4C0BAF37B9AQ33667315-3F238C7A-707E-4102-85EE-3DE450E5E76AQ33667324-D8D79C72-4A91-4692-AAF5-AE6DC97727BAQ33751847-1A30BFF6-0B83-4175-A831-A63C54E4E27DQ33804822-383788AC-82F1-4D44-9F6A-488237EAB7D6Q33915513-25EC1F45-5225-4E87-B886-B23CB0C140E8Q33950156-740C7B11-F058-4785-8746-D100CCBA4220Q33952806-160EE0CA-45C1-4D8B-8CBC-7DD88249E2D6Q34130676-1558DEA7-90F4-40E0-B1B8-D2B9C7C0350AQ34135631-E6DDFFA1-5628-4F74-AC51-7C94F97B4C50Q34373246-7D1E3F0A-9CD9-498A-B7EE-B4AA99F5C6EDQ34482045-CA05BCB2-E833-4A1A-953B-58A684AEDEEFQ34488522-58013F78-57A6-43D1-9E53-7908966D71A1Q34568941-1E4D1EAC-65C3-448B-A914-612368E46EEAQ34570975-7174E1CD-D3FA-44FA-851C-5C38F5951685Q34577381-5438060A-EAF3-4F7D-8B85-F0C54525B978Q34589866-4AC62F01-C291-4350-A47C-4F7380126328Q34736658-91047079-A761-4623-B2B1-9EA04572CAE5Q34974267-541D1397-332B-4D7F-9AF0-13E2973D0980Q35084967-22ADB3E0-E7F5-492C-A423-472C997DB67BQ35551149-57CA781F-4B51-4D63-A404-B0D530FCA336Q35564020-0A26EB18-8281-49B2-AD3C-8523DCF8AFC8Q35750137-6DCFF76A-88F4-44B7-8154-7BDD8BB24B2FQ35750140-B96B10B9-8B7A-4C76-8069-A0B5AAACC12AQ35809428-01B92C26-0FF7-40EF-BBF6-792541991DF7Q36099427-337F3A5F-D14D-4B5F-9C3A-6BB8050F44BEQ36318145-CF67BD12-D512-41D9-BEBC-B9E1358D63ECQ36429460-7DE857C6-01F9-4060-8DA9-66ACD75C6F94Q36478640-EF4797A7-2952-4869-A558-CEA8965CB82E
P2860
Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im November 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 1998
@uk
name
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@en
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@nl
type
label
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@en
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@nl
prefLabel
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@en
Cyclin D Expression Is Control ...... 3-Kinase/Akt-dependent Pathway
@nl
P2093
P2860
P356
P1476
Cyclin D expression is control ...... 3-kinase/Akt-dependent pathway
@en
P2093
A Bellacosa
P N Tsichlis
R C Muise-Helmericks
S E Malstrom
P2860
P304
29864-29872
P356
10.1074/JBC.273.45.29864
P407
P577
1998-11-01T00:00:00Z