The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
about
Role of acid-sensing ion channel 3 in sub-acute-phase inflammationA gain-of-function mutation in TRPA1 causes familial episodic pain syndromePain as a channelopathyDistinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neuronsStructural determinants of drugs acting on the Nav1.8 channelMechanical allodyniaStructure of thermally activated TRP channelsThe functional and anatomical dissection of somatosensory subpopulations using mouse geneticsUncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptorNav1.7 and other voltage-gated sodium channels as drug targets for pain reliefMu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout miceGenome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticityRET signaling is required for survival and normal function of nonpeptidergic nociceptorsThe mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.Molecular mechanisms of temperature adaptationTargeting neuroprotection as an alternative approach to preventing and treating neuropathic painCellular and Molecular Mechanisms of PainSpontaneous hair cell regeneration in the neonatal mouse cochlea in vivoSpontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse.In vivo proliferative regeneration of balance hair cells in newborn mice.Selective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.Ion channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation.TRPA1 acts as a cold sensor in vitro and in vivo.Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation.TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivoTime-lapse imaging and cell-specific expression profiling reveal dynamic branching and molecular determinants of a multi-dendritic nociceptor in C. elegans.VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch.TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.A subpopulation of nociceptors specifically linked to itchIn vivo characterization of distinct modality-specific subsets of somatosensory neurons using GCaMP.Peripheral sensory neuron injury contributes to neuropathic pain in experimental autoimmune encephalomyelitisActivity and connectivity changes of central projection areas revealed by functional magnetic resonance imaging in NaV1.8-deficient mice upon cold signaling.Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors.Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms.The chemerin receptor 23 agonist, chemerin, attenuates monosynaptic C-fibre input to lamina I neurokinin 1 receptor expressing rat spinal cord neurons in inflammatory painAquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons.Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn.Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation.MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain.Sensing hot and cold with TRP channels.
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The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
description
article publié dans la revue scientifique Science
@fr
im August 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Science
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2008
@uk
name
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@en
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@nl
type
label
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@en
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@nl
prefLabel
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@en
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@nl
P2093
P2860
P356
P1433
P1476
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
@en
P2093
A. H. Dickenson
B. Abrahamsen
C. M. Cendan
C. O. Asante
J. N. Wood
J. P. Martinez-Barbera
M. A. Nassar
P2860
P304
P356
10.1126/SCIENCE.1156916
P407
P577
2008-08-01T00:00:00Z