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KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathwaysMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDPhosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinaseTargeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenesosteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationIdentification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor familyDoubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activityJun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKLPhysical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cellsRegulation of NFATc1 in Osteoclast DifferentiationZebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in GravityGrowth of peripheral and central nervous system tumors is supported by cytoplasmic c-Fos in humans and miceA systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response.AML1 interconnected pathways of leukemogenesisFortuitous convergences: the beginnings of JUNThe expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factorAltered molecular response to adrenoreceptor-induced cardiac hypertrophy in Egr-1-deficient miceSerum response factor is essential for mesoderm formation during mouse embryogenesisFunctions of c-Jun in liver and heart developmentTRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingAlternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptorJunB is essential for mammalian placentationDasatinib as a bone-modifying agent: anabolic and anti-resorptive effects3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsGenetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival.Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice.Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations.Genome structure and thymic expression of an endogenous retrovirus in zebrafish.Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation.Role of genetic factors in the pathophysiology and management of osteoporosis.CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment.A novel mouse c-fos intronic promoter that responds to CREB and AP-1 is developmentally regulated in vivo.Cadmium osteotoxicity in experimental animals: mechanisms and relationship to human exposures.Commitment and differentiation of stem cells to the osteoclast lineage.Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling.Pivotal role of c-Fos in nitric oxide synthase 2 expression in airway epithelial cells.Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesiscFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic OsteosarcomaEssential role of RSK2 in c-Fos-dependent osteosarcoma development.Genetic disorders of the skeleton: a developmental approach
P2860
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P2860
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в грудні 1992
@uk
name
Bone and haematopoietic defects in mice lacking c-fos
@en
Bone and haematopoietic defects in mice lacking c-fos
@nl
type
label
Bone and haematopoietic defects in mice lacking c-fos
@en
Bone and haematopoietic defects in mice lacking c-fos
@nl
prefLabel
Bone and haematopoietic defects in mice lacking c-fos
@en
Bone and haematopoietic defects in mice lacking c-fos
@nl
P2093
P356
P1433
P1476
Bone and haematopoietic defects in mice lacking c-fos
@en
P2093
Agamemnon E. Grigoriadis
Catherine Ovitt
Ulrich Rüther
Uta Möhle-Steinlein
Zhao-Qi Wang
P2888
P304
P356
10.1038/360741A0
P407
P577
1992-12-01T00:00:00Z
P6179
1006209157