Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma
about
The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channelsAno1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tractAnoctamin/TMEM16 family members are Ca2+-activated Cl- channelsThe Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesisThe function of ORAOV1/LTO1, a gene that is overexpressed frequently in cancer: essential roles in the function and biogenesis of the ribosome.Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cellsInhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell LinesEtiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16ADiscovered on gastrointestinal stromal tumours 1 (DOG1) expression in non-gastrointestinal stromal tumour (GIST) neoplasms.Expression cloning of TMEM16A as a calcium-activated chloride channel subunit.Relationships linking amplification level to gene over-expression in gliomasTPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADPGenomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome.Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicingIntegrative molecular characterization of head and neck cancer cell model genomesANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines.Evolution and functional divergence of the anoctamin family of membrane proteinsAnoctamins.International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosisCharacterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screeningCharacterization of Cardiac Anoctamin1 Ca²⁺-Activated Chloride Channels and Functional Role in Ischemia-Induced ArrhythmiasGenome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancersDevelopment of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer.Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor statusHigh-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer.Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?Anoctamin and transmembrane channel-like proteins are evolutionarily related.Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancyPhenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart.The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.Phenomics of cardiac chloride channels.Role of anoctamins in cancer and apoptosis.Cytogenetic alterations and their molecular genetic correlates in head and neck squamous cell carcinoma: a next generation window to the biology of disease.Roles and regulation of phospholipid scramblases.Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistanceTMEM16A/ANO1 suppression improves response to antibody-mediated targeted therapy of EGFR and HER2/ERBB2.
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Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma
description
article
@en
im November 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2006
@uk
name
Comprehensive genome and trans ...... licon in murine oral carcinoma
@en
Comprehensive genome and trans ...... licon in murine oral carcinoma
@nl
type
label
Comprehensive genome and trans ...... licon in murine oral carcinoma
@en
Comprehensive genome and trans ...... licon in murine oral carcinoma
@nl
prefLabel
Comprehensive genome and trans ...... licon in murine oral carcinoma
@en
Comprehensive genome and trans ...... licon in murine oral carcinoma
@nl
P2093
P2860
P356
P1476
Comprehensive genome and trans ...... licon in murine oral carcinoma
@en
P2093
Kenneth S McCarty
William E Gooding
P2860
P304
P356
10.1002/GCC.20371
P577
2006-11-01T00:00:00Z