Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice - Wikidata - awgldk - TriplyDB

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

http://www.wikidata.org/entity/Q59069058

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Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive Review Pivotal roles of GM-CSF in autoimmunity and inflammation Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis?Thymus, innate immunity and autoimmune arthritis: interplay of gene and environment Rheumatoid arthritis: identifying and characterising polymorphisms using rat models Protein tyrosine phosphatase PTPN22 in human autoimmunity Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci Severe osteogenesis imperfecta in cyclophilin B-deficient mice Autoimmunity in primary T-cell immunodeficiencies.Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression Control of central and peripheral tolerance by Aire.Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.Altered B cell homeostasis and toll-like receptor 9-driven response in type 1 diabetes carriers of the C1858T PTPN22 allelic variant: implications in the disease pathogenesis Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease Update on ankylosing spondylitis: current concepts in pathogenesis.Bone formation and resorption are both increased in experimental autoimmune arthritis.A discrete affinity-driven elevation of ZAP-70 kinase activity initiates negative selection.Association of CD247 polymorphisms with rheumatoid arthritis: a replication study and a meta-analysis.Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis.Systemic but no local effects of combined zoledronate and parathyroid hormone treatment in experimental autoimmune arthritis.Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase.Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches.Toll-like receptor mediated modulation of T cell response by commensal intestinal microbiota as a trigger for autoimmune arthritis ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice.Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts Characterization of a novel and spontaneous mouse model of inflammatory arthritis.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.Altered signaling triggered by ligation of the TCR/CD3 receptor in T lymphocytes from patients with systemic lupus erythematosus: the road from anergy to autoimmunity.Association between arthritis score at the onset of the disease and long-term locomotor outcome in adjuvant-induced arthritis in rats TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response.Gut inflammation and microbiome in spondyloarthritis.Endothelial Dysfunction in Rheumatoid Arthritis: Mechanistic Insights and Correlation with Circulating Markers of Systemic Inflammation.

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Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

http://www.wikidata.org/entity/Q59069058

description

article publié dans la revue scientifique Nature

@fr

scientific article published in Nature

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature в листопаді 2003

@uk

name

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@en

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@nl

type

label

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@en

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@nl

prefLabel

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@en

Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

@nl

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Altered thymic T-cell selectio ...... s autoimmune arthritis in mice

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Hiroshi Hata

http://www.w3.org/2001/XMLSchema#string

Izumi Negishi

http://www.w3.org/2001/XMLSchema#string

Noriko Sakaguchi

http://www.w3.org/2001/XMLSchema#string

Sayuri Yamazaki

http://www.w3.org/2001/XMLSchema#string

Shimon Sakaguchi

http://www.w3.org/2001/XMLSchema#string

Syuichi Nakatsuru

http://www.w3.org/2001/XMLSchema#string

Takaji Matsutani

http://www.w3.org/2001/XMLSchema#string

Takashi Nomura

http://www.w3.org/2001/XMLSchema#string

Takeshi Takahashi

http://www.w3.org/2001/XMLSchema#string

Tomoyuki Tagami

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454-460

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scholarly article

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10.1038/NATURE02119

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426

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2003-11-01T00:00:00Z

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1030665392

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14647385

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