about
Mxi2 promotes stimulus-independent ERK nuclear translocationp38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levelsSmall Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway OncogenesBlocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelopeMxi2 sustains ERK1/2 phosphorylation in the nucleus by preventing ERK1/2 binding to phosphatases.Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteinsERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.ERK dimers and scaffold proteins: unexpected partners for a forgotten (cytoplasmic) task.ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma–lamin A complexes.
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-3058-5631
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name
Berta Casar
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Berta Casar
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Berta Casar
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Berta Casar
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type
label
Berta Casar
@ast
Berta Casar
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Berta Casar
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Berta Casar
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prefLabel
Berta Casar
@ast
Berta Casar
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Berta Casar
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Berta Casar
@nl
P106
P21
P31
P496
0000-0002-3058-5631