Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins - Wikidata - awgldk - TriplyDB

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

http://www.wikidata.org/entity/Q39900720

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MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation VRK2 inhibits mitogen-activated protein kinase signaling and inversely correlates with ErbB2 in human breast cancer Nek10 mediates G2/M cell cycle arrest and MEK autoactivation in response to UV irradiation Raf family kinases: old dogs have learned new tricks Non-stimulated, agonist-stimulated and store-operated Ca2+ influx in MDA-MB-468 breast cancer cells and the effect of EGF-induced EMT on calcium entry Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin-induced ERK signaling.Negative feedback regulation of the ERK1/2 MAPK pathway KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals Ras history: The saga continues.A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration.Signalling ballet in space and time Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21((CIP1/WAF1)) in human cancer cells.Caveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformation Lipid rafts couple class A scavenger receptors to phospholipase A2 activation during macrophage adhesion.Ras/MAPK signaling from endomembranes Cell cycle restriction is more important than apoptosis induction for RASSF1A protein tumor suppression.Morphine withdrawal stress modulates lipopolysaccharide-induced interleukin 12 p40 (IL-12p40) expression by activating extracellular signal-regulated kinase 1/2, which is further potentiated by glucocorticoids IQGAP1 and its binding proteins control diverse biological functions.Regulation of synaptic MAPK/ERK phosphorylation in the rat striatum and medial prefrontal cortex by dopamine and muscarinic acetylcholine receptors.Proteomic analysis of scaffold proteins in the ERK cascade.Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15.Dynamics of Ras complexes observed in living cells.G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes.Amphetamine increases phosphorylation of MAPK/ERK at synaptic sites in the rat striatum and medial prefrontal cortex.RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.PDE8A runs interference to limit PKA inhibition of Raf-1 ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1 Signaling dynamics of the KSR1 scaffold complex.Ras and Nox: Linked signaling networks?Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis.Heart genetics in a small package, exploiting the condensed genome of Ciona intestinalis.The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.Mechanistic principles of RAF kinase signaling.Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.The ERK Cascade: Distinct Functions within Various Subcellular Organelles.Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases.Regulating the regulator: post-translational modification of RAS Crosstalk of small GTPases at the Golgi apparatus.Growth factor signaling and memory formation: temporal and spatial integration of a molecular network.

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P2860

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

http://www.wikidata.org/entity/Q39900720

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Ras subcellular localization d ...... ilization of scaffold proteins

@en

Ras subcellular localization d ...... lization of scaffold proteins.

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type

label

Ras subcellular localization d ...... ilization of scaffold proteins

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Ras subcellular localization d ...... lization of scaffold proteins.

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prefLabel

Ras subcellular localization d ...... ilization of scaffold proteins

@en

Ras subcellular localization d ...... lization of scaffold proteins.

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Molecular and Cellular Biology

P1476

Ras subcellular localization d ...... ilization of scaffold proteins

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P2093

Adán Pinto

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Lorena Agudo-Ibáñez

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María T Berciano

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Robert E Lewis

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Victoria Sanz-Moreno

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P2860

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

cPLA2 is phosphorylated and activated by MAP kinase

Cell-type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptor

Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors

p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels

An acylation cycle regulates localization and activity of palmitoylated Ras isoforms

H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis.

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

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1338-1353

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scholarly article

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10.1128/MCB.01359-08

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5

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29

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Imanol Arozarena

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2008-12-29T00:00:00Z

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23711763

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19114553

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2643815

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