ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.
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When lamins go bad: nuclear structure and diseaseCardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- miceLamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyERK5 and Cell Proliferation: Nuclear Localization Is What MattersRegulation of lamin properties and functions: does phosphorylation do it all?Lipin1 Regulates Skeletal Muscle Differentiation through Extracellular Signal-regulated Kinase (ERK) Activation and Cyclin D Complex-regulated Cell Cycle Withdrawal.Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.Growth arrest signaling of the Raf/MEK/ERK pathway in cancer.Synthesis, transport and incorporation into the nuclear envelope of A-type lamins and inner nuclear membrane proteins.The nuclear envelope environment and its cancer connections.Cellular mechanosensing: getting to the nucleus of it all.The role of nuclear lamin B1 in cell proliferation and senescence.Lamins at a glance.The cellular mastermind(?)-mechanotransduction and the nucleus.Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome.Gan-Lu-Yin Inhibits Proliferation and Migration of Murine WEHI-3 Leukemia Cells and Tumor Growth in BALB/C Allograft Tumor Model.The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.Defined spatiotemporal features of RAS-ERK signals dictate cell fate in MCF-7 mammary epithelial cells.Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases.Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease.Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathiesLamins at the crossroads of mechanosignalingCauses and consequences of nuclear envelope alterations in tumour progression.Mechanosensing by the nucleus: From pathways to scaling relationships.The secret life of kinases: functions beyond catalysisA truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.Arabidopsis thaliana mitogen-activated protein kinase 6 is involved in seed formation and modulation of primary and lateral root development.Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone.Rb gets ERK'd by the competition.Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging.A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.
P2860
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P2860
ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
ERK1/2 MAP kinases promote cel ...... inoblastoma-lamin A complexes.
@en
type
label
ERK1/2 MAP kinases promote cel ...... inoblastoma-lamin A complexes.
@en
prefLabel
ERK1/2 MAP kinases promote cel ...... inoblastoma-lamin A complexes.
@en
P2093
P2860
P50
P356
P1476
ERK1/2 MAP kinases promote cel ...... tinoblastoma-lamin A complexes
@en
P2093
Berta Casar
Fernando Calvo
Javier Rodríguez
José M González
Piero Crespo
Vicente Andrés
P2860
P304
P356
10.1083/JCB.201004067
P407
P577
2010-11-01T00:00:00Z