about
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathwayAn essential function for NBS1 in the prevention of ataxia and cerebellar defectsBRCA2 is required for neurogenesis and suppression of medulloblastomaNibrin functions in Ig class-switch recombinationIdentification of differential gene expression in in vitro FSH treated pig granulosa cells using suppression subtractive hybridization.Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.Ataxia-telangiectasia and related diseases.Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.Mouse models of DNA double-strand break repair and neurological diseaseEpidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis.Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms.Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks.ATR maintains select progenitors during nervous system development.RINT1 functions as a multitasking protein at the crossroads between genomic stability, ER homeostasis, and autophagy.Poly(ADP-ribose) polymerase-1, a novel partner of progesterone receptors in endometrial cancer and its precursors.ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis.An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability.BRCA2 function and the central nervous system.Precision medicine meets the DNA damage response in pancreatic cancer.Importance of organoids for personalized medicinePancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks
P50
Q28506694-2B24EFFF-012E-41C5-B51B-29EF64CC447EQ28507300-96563313-991F-44E1-B704-DBDF6855739DQ28590758-7F2E1952-143D-45A3-948D-C2C0DAE2292DQ28594821-86ED8B98-4E35-49A3-B1C9-1A26F5CE54FAQ33249321-B1C8EA4E-F084-4039-B973-5C1072A4D673Q34919494-FB95AFA0-B45D-4038-A1B2-F2FACF8F9730Q36617706-70CAB8F9-A90D-449A-B12B-FDE84230CEA3Q37100889-408E2E2C-7B3C-4FEC-BC34-8B049F467DE8Q37155146-73CB4382-9B18-442F-A7D0-4952411EDBFDQ37268929-345E3E87-918F-4E85-B14A-4233348BA819Q37354009-3E4C9EF3-EEAF-4171-A2C1-0901D0CE1610Q39030536-16D66FD0-AE35-43F1-A436-53885E9F3978Q40212438-D1C759A5-44F0-444F-876E-D150F00C42DEQ41767755-1F46F848-7758-4831-8CEC-A3208A2C8AD1Q42390461-66E9A331-0971-4C9B-92AE-A67D7C3B27DDQ44763078-E2F62354-4BDE-4F5E-BCA4-D11646C0BCD9Q46518098-A4DAD199-6A5D-477B-8774-5FACD8E27001Q52571600-8D5EC513-0EF6-41D3-BDAC-31CB2207DF72Q52943096-0C9A15A4-6218-4D55-B0A7-F9F59B2F3181Q53530318-6FC368C7-FA7D-4F4C-8429-C2A4C0259695Q55343373-130A80CE-066A-4EEA-A7A8-702F7B7458BEQ60609556-0B0446CD-E0A4-4B00-A3EF-9F4C9BE7DED7Q93002343-49AACF5B-2C1C-4B9D-B07B-21D082CA4CF4
P50
description
researcher ORCID ID = 0000-0002-8142-3878
@en
wetenschapper
@nl
name
Pierre-Olivier Frappart
@ast
Pierre-Olivier Frappart
@en
Pierre-Olivier Frappart
@es
Pierre-Olivier Frappart
@fr
Pierre-Olivier Frappart
@nl
type
label
Pierre-Olivier Frappart
@ast
Pierre-Olivier Frappart
@en
Pierre-Olivier Frappart
@es
Pierre-Olivier Frappart
@fr
Pierre-Olivier Frappart
@nl
prefLabel
Pierre-Olivier Frappart
@ast
Pierre-Olivier Frappart
@en
Pierre-Olivier Frappart
@es
Pierre-Olivier Frappart
@fr
Pierre-Olivier Frappart
@nl
P106
P21
P31
P496
0000-0002-8142-3878