about
Nijmegen breakage syndrome (NBS)Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesIgH chain class switch recombination: mechanism and regulationA systematic proteomic study of irradiated DNA repair deficient Nbn-miceATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaksUpdate on the hyper immunoglobulin M syndromesDual functions of Nbs1 in the repair of DNA breaks and proliferation ensure proper V(D)J recombination and T-cell development.A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutationThe Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevisThe MRN complex in double-strand break repair and telomere maintenance.DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.Chromatin remodeling, DNA damage repair and aging.Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair.Mechanism and regulation of class switch recombinationp53 represses class switch recombination to IgG2a through its antioxidant functionRole of genomic instability and p53 in AID-induced c-myc-Igh translocations.DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation.APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.CtIP promotes microhomology-mediated alternative end joining during class-switch recombinationDNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBSMultiple functions of MRN in end-joining pathways during isotype class switchingDefective signal joint recombination in fanconi anemia fibroblasts reveals a role for Rad50 in V(D)J recombinationNon-homologous end joining in class switch recombination: the beginning of the endIdentification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria.The MRE11 complex: starting from the ends.Primary immunodeficiencies associated with DNA-repair disorders.DNA double-strand break repair, immunodeficiency and the RIDDLE syndrome.DNA repair: the link between primary immunodeficiency and cancer.Molecular nature of radiation injury and DNA repair disorders associated with radiosensitivity.ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks.The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions.ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.
P2860
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P2860
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/02/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/02/01)
@nl
наукова стаття, опублікована в лютому 2005
@uk
name
Nibrin functions in Ig class-switch recombination
@ast
Nibrin functions in Ig class-switch recombination
@en
Nibrin functions in Ig class-switch recombination
@nl
type
label
Nibrin functions in Ig class-switch recombination
@ast
Nibrin functions in Ig class-switch recombination
@en
Nibrin functions in Ig class-switch recombination
@nl
prefLabel
Nibrin functions in Ig class-switch recombination
@ast
Nibrin functions in Ig class-switch recombination
@en
Nibrin functions in Ig class-switch recombination
@nl
P2093
P2860
P356
P1476
Nibrin functions in Ig class-switch recombination
@en
P2093
Andreas Radbruch
Gabriele Hildebrand
Karl Sperling
Martin Digweed
Rainer Christine
Sven Kracker
Yvonne Bergmann
Zhao-Qi Wang
P2860
P304
P356
10.1073/PNAS.0409191102
P407
P577
2005-02-01T00:00:00Z