about
ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localizationIsolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptorMolecular cloning and functional expression of a new human CC-chemokine receptor geneNucleotide sequence of a human cannabinoid receptor cDNAAgonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226Tissue distribution of the opioid receptor-like (ORL1) receptorFunctional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domainPharmacological characterization of human NPFF(1) and NPFF(2) receptors expressed in CHO cells by using NPY Y(1) receptor antagonistsThe high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptorPhysical association between neuropeptide FF and micro-opioid receptors as a possible molecular basis for anti-opioid activityNeuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cellsRecognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioidsFunctional characterization of a human receptor for neuropeptide FF and related peptidesLoss of morphine reward and dependence in mice lacking G protein-coupled receptor kinase 5.Heterologous regulation of Mu-opioid (MOP) receptor mobility in the membrane of SH-SY5Y cells.Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptorsIdentification and functional characterization of the phosphorylation sites of the neuropeptide FF2 receptor.Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.Opioid-modulating peptides: mechanisms of action.Structure-activity relationships of neuropeptide FF and related peptidic and non-peptidic derivatives.Opioid-modulating properties of the neuropeptide FF system.N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time.Solubilization and reconstitution of the mu-opioid receptor expressed in human neuronal SH-SY5Y and CHO cells.Modulation by neuropeptide FF of the interaction of mu-opioid (MOP) receptor with G-proteins.Neuropeptide FF-sensitive confinement of mu opioid receptor does not involve lipid rafts in SH-SY5Y cells.Staurosporine differentiation of NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells induces selectivity of NPFF activity towards opioid receptors.Anti-opioid activities of NPFF1 receptors in a SH-SY5Y model.Anti-analgesia of a selective NPFF2 agonist depends on opioid activity.Phosphoproteomic analysis of the mouse brain mu-opioid (MOP) receptor.[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor.Neanderthal and Denisova tooth protein variants in present-day humans.Pharmacological characterization of the mouse NPFF2 receptor.Structure-activity relationships of neuropeptide FF: role of C-terminal regions.Characterization, solubilization and purification of an opioid receptor from the brain of the frog Rana ridibunda.Anti-opioid effects of neuropeptide FF receptors in the ventral tegmental area.Different domains of the ORL1 and kappa-opioid receptors are involved in recognition of nociceptin and dynorphin A.Development of a peptidomimetic antagonist of neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia.Distinct mechanisms for activation of the opioid receptor-like 1 and kappa-opioid receptors by nociceptin and dynorphin A.NPYFa, A Chimeric Peptide of Met-Enkephalin, and NPFF Induces Tolerance-Free Analgesia.
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description
onderzoeker
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researcher ORCID ID = 0000-0003-1543-5624
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name
C Mollereau
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C Mollereau
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C Mollereau
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label
C Mollereau
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C Mollereau
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C Mollereau
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prefLabel
C Mollereau
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C Mollereau
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C Mollereau
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P106
P31
P496
0000-0003-1543-5624