about
Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data.Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population.Visualizing reaction pathways in photoactive yellow protein from nanoseconds to secondsNovel approach to classifying patients with pulmonary arterial hypertension using cluster analysis.Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).Quantifying ligand bias at seven-transmembrane receptors.Multiple ligand-specific conformations of the β2-adrenergic receptorTotal chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunitTherapeutic potential of β-arrestin- and G protein-biased agonists.Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension.Abnormalities in hyperpolarized (129)Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease.The β-Arrestins: Multifunctional Regulators of G Protein-coupled ReceptorsBiased agonism as a mechanism for differential signaling by chemokine receptors.Clinical and echocardiographic predictors of mortality in acute pulmonary embolism.What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling.Quantitative analysis of hyperpolarized 129 Xe gas transfer MRI.GPCR desensitization: Acute and prolonged phases.Echocardiography in the Risk Assessment of Acute Pulmonary Embolism.The influence of angle of insonation and target depth on speckle-tracking strain.Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors.Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach.Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry.Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views.Biased signalling: from simple switches to allosteric microprocessors.Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein.Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension.C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways.Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension.Quantifying biased agonism: understanding the links between affinity and efficacy.Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9The Role of G Protein-Coupled Receptors in the Right Ventricle in Pulmonary HypertensionClinical Features and Outcomes of Patients with Sarcoidosis-associated Pulmonary HypertensionRight Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent SoftwareChemokine Signaling in Allergic Contact Dermatitis: Toward Targeted TherapiesHyperpolarized 129 Xe gas transfer MRI: the transition from 1.5T to 3TClinical Utility and Prognostic Value of Right Atrial Function in Pulmonary HypertensionVascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary HypertensionThe role of chemokines and chemokine receptors in pulmonary arterial hypertension
P50
Q30915692-114F153D-B115-4BB0-93DB-6985570D9EA2Q33737579-451A4912-0622-4AC9-A895-D03B236BFCA6Q33771625-12F6E018-00D7-4544-BB4F-3809A7BEA0D7Q33788539-F4A69864-E05C-4A39-B70F-D003552E2F7BQ34093722-3CF31421-EADD-4B8C-A239-81D119C2BBBDQ35188090-45D4C6CD-F861-4C3D-9C9A-0F5FF0F3B71CQ36115098-2BE22011-2AB7-4D4B-AC42-24DDF2E7252AQ36393535-D7058791-BB7D-4E0D-B6F0-B7061DB4F75CQ36773331-669165F3-04CE-4F34-8AFA-705E02E19053Q36777530-6CDD7A05-ACF8-4F37-8F5E-05D057C81A3FQ36881766-FDEE0940-2015-401D-B670-402E61ED170AQ36884777-4BFE5E4C-3E43-4802-8454-5749AE3ABFE8Q37368610-FA8C8734-4491-4836-B959-D4321534D7E0Q37377982-B3511C3C-41EC-42B9-BF9E-9A293007D80BQ38275330-53DD5A17-ECC2-4CE3-B312-D0AA43AE218AQ38851010-7DA9ED64-01B5-4F94-8571-6345CB4FD36EQ39110070-A875BD02-B65C-4EEE-BF99-671ECE81E9DDQ39139093-0C3A4624-231F-4334-BDA8-3DBAAA415F69Q41473737-474C8968-FF90-4142-A637-8B2D31FF073CQ41883529-84D38E2E-3B9D-4979-9485-82C3D17B7D28Q41902757-E14A8704-C88D-44C0-B409-FE81436DA437Q42316573-BE75E06C-9777-41DA-ABDF-84626E4A4926Q43195607-1631A6B4-A958-410B-BEA7-BCAAE3483DB0Q46286823-A480CF98-2E6B-4EB2-81DA-01ACA3727602Q47231111-8FC42B56-41C2-41E5-96E5-AC6F90568BB8Q50488930-455D6E59-F334-417F-9BFD-FCB6A97FC47DQ50777417-28E0CC14-192B-45C3-9734-3C6FD6D3E00DQ50970453-930C16B0-3F34-4835-9CB7-789E53E5071FQ53103374-BDB30A3F-1514-45CB-9FF8-A225E2D81705Q53119503-7E4B099B-689E-4EEA-A5AF-3FF6DFB61A20Q58435171-D5DBB885-E65B-4C79-BC9D-AE666D1F4A8EQ60950964-A16003D0-BDBE-4F2D-91F9-0093BC7E78AAQ64109876-78AA0343-7AC1-469D-8A82-5DD2A5185849Q88015752-04B29B21-71EF-4A63-96B3-AA229D79FB93Q89233358-197453E2-9E84-464F-8BE5-9316976891F9Q90336806-9F15297A-2992-465C-B293-BF9FCD5548DBQ90667447-982A2C47-B156-4B3C-BC69-D4375C0FAAEEQ90759789-F5CA27E6-D002-42DD-A942-CCA120A410D7Q90857555-67E2F76C-B833-4CE2-8212-5CACD8D4DEA7Q92536966-55F5AB7B-80E4-4EE0-971C-EFD57C8F9B8B
P50
description
researcher ORCID ID = 0000-0002-3443-5040
@en
wetenschapper
@nl
name
Sudarshan Rajagopal
@ast
Sudarshan Rajagopal
@en
Sudarshan Rajagopal
@es
Sudarshan Rajagopal
@nl
type
label
Sudarshan Rajagopal
@ast
Sudarshan Rajagopal
@en
Sudarshan Rajagopal
@es
Sudarshan Rajagopal
@nl
prefLabel
Sudarshan Rajagopal
@ast
Sudarshan Rajagopal
@en
Sudarshan Rajagopal
@es
Sudarshan Rajagopal
@nl
P31
P496
0000-0002-3443-5040