Reversine increases the plasticity of lineage-committed mammalian cellsReversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cellsDedifferentiation of lineage-committed cells by a small moleculeThe synthetic purine reversine selectively induces cell death of cancer cellsDissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversineReversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy"Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonistsReversine induces cell cycle arrest, polyploidy, and apoptosis in human breast cancer cells.Reversine, a 2,6-disubstituted purine, as an anti-cancer agent in differentiated and undifferentiated thyroid cancer cells.The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells.Induction of growth arrest and polycomb gene expression by reversine allows C2C12 cells to be reprogrammed to various differentiated cell types.Reversine enhances generation of progenitor-like cells by dedifferentiation of annulus fibrosus cells.Reversine stimulates adipocyte differentiation and downregulates Akt and p70(s6k) signaling pathways in 3T3-L1 cells.Beneficial effects of reversine on in vitro development of miniature pig somatic cell nuclear transfer embryos.Reversine inhibits spontaneous synaptic transmission in cultured rat hippocampal neurons.Reversine promotes porcine muscle derived stem cells (PMDSCs) differentiation into female germ-like cells.Preferential killing of p53-deficient cancer cells by reversine.Reversine increases multipotent human mesenchymal cells differentiation potential
P921
Q24669793-E6CAD417-FEF1-4079-944C-DAF0C95BB307Q27650627-3610583A-BBD9-474F-BEB3-FEE77D84F7B1Q28238479-F6043834-60A6-4DBF-A85E-2F98FFCB2D2FQ28267191-DB3363C9-CE90-4E1D-8682-5B1325121512Q34026669-DABCC8B0-E677-47E8-BFC1-4F82965A3E1BQ35822375-F9B6B1AB-5A97-4332-AB2F-185515950A41Q36327179-4EC8F118-CC57-488E-8A6C-36719489DB41Q39290064-3272A794-52AE-4898-A086-CAF539166B52Q39369159-C08D406F-9B7A-4AB4-A41D-DFFED589A1D9Q40056453-3BDB38E9-6534-4E78-B1A1-8E55048012C4Q40059564-5E08F47E-7570-4E72-B29E-340F4BBF758AQ42412059-AD4E3C91-1E10-4208-A242-2CD1009CC5D1Q42828463-4A308512-C67C-4334-8D77-D83179303EA8Q43183385-F52D1A85-B998-4A25-85CF-A87A1AD69185Q48295932-804FF328-4CCF-484C-B767-E55835473145Q48643675-F9631586-1784-4B7D-8BD1-93D477BC64F8Q54510509-1F43CF2F-538F-440B-A0C7-64B47196DAA8Q82331876-DC0D7A82-4CD3-4E98-962A-C09850B62559
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Reversine
@vi
Reverzin
@sh
Reverzin
@sr
reversina
@ca
reversine
@en
رورسین
@azb
رورسین
@fa
リバーシン
@ja
type
label
Reversine
@vi
Reverzin
@sh
Reverzin
@sr
reversina
@ca
reversine
@en
رورسین
@azb
رورسین
@fa
リバーシン
@ja
altLabel
2-(4-morpholinoanilino)-6-cyclohexylaminopurine
@en
N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine
@en
prefLabel
Reversine
@vi
Reverzin
@sh
Reverzin
@sr
reversina
@ca
reversine
@en
رورسین
@azb
رورسین
@fa
リバーシン
@ja
P592
P6366
P661
P662
P683
P117
P1579
P2067
P231
656820-32-5
P232
P233
C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
P234
1S/C21H27N7O/c1-2-4-15(5-3-1)2 ...... 10-13H2,(H3,22,23,24,25,26,27)
P235
ZFLJHSQHILSNCM-UHFFFAOYSA-N
P2566
100.164.070
P274
P3117
DTXSID8041113
P592
CHEMBL188343
P6366
2779018643
P652
Z499CLJ023