about
Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disordersLack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's diseaseElevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic miceGenetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice.The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated AβCerebrospinal fluid soluble TREM2 in aging and Alzheimer's diseaseThe Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathwayDocosahexaenoic acid stimulates non-amyloidogenic APP processing resulting in reduced Abeta levels in cellular models of Alzheimer's disease.Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice.Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model.Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid.Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells.Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer's Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration.Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ.Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpressionGlial activation and inflammation along the Alzheimer's disease continuumCSF sTREM2 and Tau Work Together in Predicting Increased Temporal Lobe Atrophy in Older Adults
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P50
description
investigador
@es
onderzoeker
@nl
researcher
@en
name
lars nilsson
@ast
lars nilsson
@en
lars nilsson
@es
lars nilsson
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type
label
lars nilsson
@ast
lars nilsson
@en
lars nilsson
@es
lars nilsson
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prefLabel
lars nilsson
@ast
lars nilsson
@en
lars nilsson
@es
lars nilsson
@nl
P106
P1153
35592478900
P2798
P31
P496
0000-0002-8362-1042