Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.
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Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's diseaseInflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's diseaseEnvironmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseasesNeuroinflammation in Alzheimer's diseaseAlzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasisInflammation and Alzheimer's diseaseInterleukin-1 in the genesis and progression of and risk for development of neuronal degeneration in Alzheimer's diseaseIncreased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarkerRole of the 5' untranslated region (UTR) in the tissue-specific regulation of rat tryptophan hydroxylase gene expression by stressSynthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholPhysiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators.In vitro selection of an RNA sequence that interacts with high affinity with thymidylate synthase.Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting.Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia.Temporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: implications for the regulation of gene expression.Iron redistribution as a therapeutic strategy for treating diseases of localized iron accumulation.MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons.A GG nucleotide sequence of the 3' untranslated region of amyloid precursor protein mRNA plays a key role in the regulation of translation and the binding of proteinsThe pervasiveness of interleukin-1 in alzheimer pathogenesis: a role for specific polymorphisms in disease risk.MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients.Post-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins.Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42)Neuroinflammation in Alzheimer's disease and prion disease.Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells.The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesisIncreased production of inflammatory cytokines in mild cognitive impairment.Alzheimer's Disease: Fatty Acids We Eat may be Linked to a Specific Protection via Low-dose Aspirin.Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology.Paeonol Protects Memory after Ischemic Stroke via Inhibiting β-Secretase and Apoptosis.Trisomy 21 and the brainThe regulation of AβPP expression by RNA-binding proteinsSimultaneous gene expression analysis of steady-state and actively translated mRNA populations from osteosarcoma MG-63 cells in response to IL-1alpha via an open expression analysis platform.Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug developmentTargeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases.BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's diseaseToll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology.The blockage of the Nogo/NgR signal pathway in microglia alleviates the formation of Aβ plaques and tau phosphorylation in APP/PS1 transgenic mice.Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.Phenserine.
P2860
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P2860
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Translation of the alzheimer a ...... untranslated region sequences.
@en
Translation of the alzheimer a ...... untranslated region sequences.
@nl
type
label
Translation of the alzheimer a ...... untranslated region sequences.
@en
Translation of the alzheimer a ...... untranslated region sequences.
@nl
prefLabel
Translation of the alzheimer a ...... untranslated region sequences.
@en
Translation of the alzheimer a ...... untranslated region sequences.
@nl
P2093
P356
P1476
Translation of the alzheimer a ...... -untranslated region sequences
@en
P2093
P304
P356
10.1074/JBC.274.10.6421
P407
P50
P577
1999-03-01T00:00:00Z