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Structures of active and latent PAI-1: a possible stabilizing role for chloride ionsDemonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885The design, synthesis, and biological evaluation of PIM kinase inhibitorsDiscovery of XL413, a potent and selective CDC7 inhibitorThe design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitorsLiver X receptor (LXR) partial agonists: biaryl pyrazoles and imidazoles displaying a preference for LXRβThe complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibitionAn essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58QD221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidineCrystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilisStructure-based design of inhibitors specific for bacterial thymidylate synthaseCrystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibitionCan mosquitoes be bitten? A new hope for anti-malarial drug design.
P50
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P50
description
researcher
@en
wetenschapper
@nl
name
T J Stout
@en
T J Stout
@nl
type
label
T J Stout
@en
T J Stout
@nl
prefLabel
T J Stout
@en
T J Stout
@nl
P106
P31
P496
0000-0001-5260-5149