A modular and flexible ESC-based mouse model of pancreatic cancer.
about
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.Diabetes, pancreatic cancer, and metformin therapy.A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis.A combinatorial strategy for treating KRAS-mutant lung cancerMitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine effortsStromal biology and therapy in pancreatic cancer: a changing paradigm.MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination.TGF-β Tumor Suppression through a Lethal EMT.HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.Engineering PTEN-L for Cell-Mediated Delivery.Using the GEMM-ESC strategy to study gene function in mouse models.Engineering of Conditional Class I Hdac Knockout Mice and Generation of a Time-Spatial Knockout by a Dual Recombination System.Arid1a restrains Kras-dependent changes in acinar cell identity.
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A modular and flexible ESC-based mouse model of pancreatic cancer.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2014
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A modular and flexible ESC-based mouse model of pancreatic cancer.
@en
A modular and flexible ESC-based mouse model of pancreatic cancer.
@nl
type
label
A modular and flexible ESC-based mouse model of pancreatic cancer.
@en
A modular and flexible ESC-based mouse model of pancreatic cancer.
@nl
prefLabel
A modular and flexible ESC-based mouse model of pancreatic cancer.
@en
A modular and flexible ESC-based mouse model of pancreatic cancer.
@nl
P2093
P2860
P356
P1433
P1476
A modular and flexible ESC-based mouse model of pancreatic cancer
@en
P2093
Anna Saborowski
Benedikt Bosbach
David S Klimstra
John P Morris
Lukas E Dow
Michael Saborowski
Scott W Lowe
P2860
P356
10.1101/GAD.232082.113
P577
2014-01-01T00:00:00Z