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Q37332317-6910DE1B-95CE-43A3-B48E-51EAFC698341
Q37332317-6910DE1B-95CE-43A3-B48E-51EAFC698341
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37332317-6910DE1B-95CE-43A3-B48E-51EAFC698341
Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.
P2860
Q37332317-6910DE1B-95CE-43A3-B48E-51EAFC698341
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37332317-6910DE1B-95CE-43A3-B48E-51EAFC698341
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Statement
wasDerivedFrom
e9a858fc9f085094242f9576d3df9bab5df3374f
P2860
A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.