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Q39703203-5D8537EF-9F6B-4AD6-8A78-AA3F4502AEDC
Q39703203-5D8537EF-9F6B-4AD6-8A78-AA3F4502AEDC
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39703203-5D8537EF-9F6B-4AD6-8A78-AA3F4502AEDC
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).
P2860
Q39703203-5D8537EF-9F6B-4AD6-8A78-AA3F4502AEDC
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39703203-5D8537EF-9F6B-4AD6-8A78-AA3F4502AEDC
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wasDerivedFrom
bc914fc80dae5ac4f2bb58344bf9c6f892f726e7
P2860
A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices.