about
P688
A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transitionSelective inhibition of BET bromodomainsBromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cellsBrd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progressionPhospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targetingBrd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelABrd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause releaseBRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domainThe Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
P921
Q22254769-92B3BFA3-B62D-47C8-A7F6-798778679EA7Q24301009-AB3427AA-A809-42CA-B799-B9B5F4DB881AQ24301441-3B5332E4-8827-499A-8527-A7F017126349Q24301464-C2E89209-1B5C-495D-8A1D-A30EDBB2287DQ24308867-3B340DDA-1751-43C3-BD0F-E1B29412F220Q24310313-C5D932A4-B8B7-41AD-A5B3-A30F5C28E03AQ24315005-1599BD16-F6C9-46BC-A478-8D00A5D59211Q28116760-7F27524C-082A-4155-8658-E01F29E741C7Q35096586-188D4549-9562-41BA-AE3A-42D8D570A5D1Q47116460-D4E70C87-4F78-4BF9-888C-358CB569D1E7
P921
description
Säugetierprotein
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Bromodomain containing 4
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Bromodomain containing 4
@en
type
label
Bromodomain containing 4
@en
altLabel
BRD4
@en
Protein HUNK1
@en
bromodomain-containing protein 4
@en
chromosome-associated protein
@en
mitotic chromosome-associated protein
@en
prefLabel
Bromodomain containing 4
@en
P129
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P680
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P705
P352
P31
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P637
NP_001317313
NP_001366220
NP_001366221
P638
P680
P682
P702
P703
P705
ENSP00000263377
ENSP00000353112
ENSP00000360901
ENSP00000470108
ENSP00000470481
ENSP00000471240
ENSP00000486621