Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
about
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SKBrd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelASelective inhibition of BET bromodomainsDown-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibitionThe role of human bromodomains in chromatin biology and gene transcriptionEpimutational profile of hematologic malignancies as attractive target for new epigenetic therapiesOpen access chemical probes for epigenetic targetsPreparing the first responders: building the inflammatory transcriptome from the ground upChromatin targeting drugs in cancer and immunityGetting up to speed with transcription elongation by RNA polymerase IIStructures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic ResolutionSuppression of inflammation by a synthetic histone mimicA Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in CardiomyocytesIdentification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived HitStructure-Guided Design of Potent Diazobenzene Inhibitors for the BET BromodomainsAcetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase InhibitorsBinding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylationSelective Chemical Modulation of Gene Transcription Favors Oligodendrocyte Lineage ProgressionEpigenome-modifying tools in asthmaBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesStructural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3Targeting bromodomains: epigenetic readers of lysine acetylationThe mechanisms behind the therapeutic activity of BET bromodomain inhibitionFunctions of BET proteins in erythroid gene expressionBromodomains: Translating the words of lysine acetylation into myelin injury and repairBET domain co-regulators in obesity, inflammation and cancerKeap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain ProteinBrd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expressionBET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.Drug Discovery Targeting Bromodomain-Containing Protein 4.Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.Minireview: The versatile roles of lysine deacetylases in steroid receptor signalingIntegration of small-molecule discovery in academic biomedical researchBromodomain protein 4 is a novel predictor of survival for gastric carcinomaWriters and readers of histone acetylation: structure, mechanism, and inhibitionBET proteins are a key component of immunoglobulin gene expression.Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice.Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.Protein kinase D3 is essential for prostratin-activated transcription of integrated HIV-1 provirus promoter via NF-κB signaling pathway
P2860
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P2860
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@ast
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en-gb
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@nl
type
label
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@ast
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en-gb
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@nl
prefLabel
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@ast
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en-gb
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@nl
P2093
P2860
P921
P3181
P356
P1476
Brd4 coactivates transcription ...... fic binding to acetylated RelA
@en
P2093
Keiko Ozato
Lin-Feng Chen
Ming-Ming Zhou
Xiao-Dong Yang
P2860
P304
P3181
P356
10.1128/MCB.01365-08
P407
P577
2009-03-01T00:00:00Z