Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression
about
Mitotic bookmarking by transcription factorsSelective inhibition of BET bromodomainsPhospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targetingHistone recognition and large-scale structural analysis of the human bromodomain familyBrd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause releaseThe structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylationSKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivationNUT midline carcinomaGene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionBromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System TumorsBromodomain proteins in HIV infectionSmall-molecule inhibitors of the Myc oncoproteinBenzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET familyBET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor ModelsEpigenetic modulators as therapeutic targets in prostate cancerResetting a functional G1 nucleus after mitosisBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesThe mechanisms behind the therapeutic activity of BET bromodomain inhibitionTargeting BET bromodomains for cancer treatmentBET domain co-regulators in obesity, inflammation and cancerTwo faces of brd4: mitotic bookmark and transcriptional lynchpinBromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replicationThe testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatidsCell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cellsPhosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomesCyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytesTargeting MYC dependence in cancer by inhibiting BET bromodomainsRNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaDrug Discovery Targeting Bromodomain-Containing Protein 4.Characterization of BRD4 during mammalian postmeiotic sperm development.A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repressionBromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.Pleiotrophin antagonizes Brd2 during neuronal differentiation.Papillomavirus interaction with cellular chromatin.BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma.Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.
P2860
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P2860
Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@ast
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en-gb
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@nl
type
label
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@ast
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en-gb
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@nl
prefLabel
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@ast
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en-gb
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@nl
P2093
P2860
P921
P3181
P356
P1476
Brd4 recruits P-TEFb to chromo ...... ion and cell cycle progression
@en
P2093
Qiang Zhou
Zhiyuan Yang
P2860
P304
P3181
P356
10.1128/MCB.01020-07
P407
P577
2008-02-01T00:00:00Z