SMG6 nonsense mediated mRNA decay factor

SMG6 nonsense mediated mRNA decay factor

Item
http://www.wikidata.org/entity/Q21107304
SMG6
P688
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathwayFunctional conservation of the telomerase protein Est1p in humansPhosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decayThe human RNA surveillance factor UPF1 is required for S phase progression and genome stabilitySMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoanSMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cellsA human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressedAn anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalizationTelomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome endsProtein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomeraseRegulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis
P921

SMG6 nonsense mediated mRNA decay factor

Item
http://www.wikidata.org/entity/Q21107304
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
SMG6 nonsense mediated mRNA decay factor
@en
SMG6 nonsense mediated mRNA decay factor
@nl
type
label
SMG6 nonsense mediated mRNA decay factor
@en
SMG6 nonsense mediated mRNA decay factor
@nl
altLabel
EST1 telomerase component homolog A
@en
EST1-like protein A
@en
SMG6
@en
Smg-6 homolog
@en
ever shorter telomeres 1A
@en
hSmg5/7a
@en
smg-6 homolog, nonsense mediated mRNA decay factor
@en
telomerase subunit EST1A
@en
telomerase-binding protein EST1A
@en
prefLabel
SMG6 nonsense mediated mRNA decay factor
@en
SMG6 nonsense mediated mRNA decay factor
@nl
P31
P352
P361
P527
P637
P638
P680
P681
P682
P702
P703
P705
P352
P637
P638
P31
P352
P361
P527
P637
P638
P680
P681
P682
P702
P703
P705