A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed
about
Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoHuman UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replicationA human telomerase holoenzyme protein required for Cajal body localization and telomere synthesisCrystallization and preliminary X-ray analysis of the PIN domain of human EST1ATERRA: telomeric repeat-containing RNAHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationNonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathwaysStructures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complexA GFP-based reporter system to monitor nonsense-mediated mRNA decayMulti-OMICs and Genome Editing Perspectives on Liver Cancer Signaling NetworksThe Chp1–Tas3 core is a multifunctional platform critical for gene silencing by RITSSaccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex.A three-state model for the regulation of telomerase by TERRA and hnRNPA1Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome endsProtein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomeraseRegulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainSwitching human telomerase on and off with hPOT1 protein in vitroThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisTetrahymena telomerase is active as a monomer.Yeast telomerase RNA: a flexible scaffold for protein subunits.Human telomerase: biogenesis, trafficking, recruitment, and activation.Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegansThe biogenesis and regulation of telomerase holoenzymesThe non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomeraseMolecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways.A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.Regulated assembly and disassembly of the yeast telomerase quaternary complex.A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies.Identification and characterization of the Schizosaccharomyces pombe TER1 telomerase RNA.RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.Evidence for age as a modifier of genetic associations for lipid levels.Telomerase activation after recruitment in fission yeast.Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.Schizosaccharomyces pombe Ccq1 and TER1 bind the 14-3-3-like domain of Est1, which promotes and stabilizes telomerase-telomere association.Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells.
P2860
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P2860
A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed
description
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im April 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/04/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/04/01)
@nl
наукова стаття, опублікована у квітні 2003
@uk
مقالة علمية (نشرت في أبريل 2003)
@ar
name
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@ast
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@en
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@nl
type
label
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@ast
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@en
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@nl
prefLabel
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@ast
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@en
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@nl
P2093
P921
P3181
P1433
P1476
A human homolog of yeast Est1 ...... mosome ends when overexpressed
@en
P2093
Markus Nabholz
Matthias Höss
Patrick Reichenbach
Philipp Bucher
P304
P3181
P356
10.1016/S0960-9822(03)00173-8
P407
P577
2003-04-01T00:00:00Z