VHL type 2B mutations retain VBC complex form and function
about
State of the science: an update on renal cell carcinomaIdentification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinomaGenetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein.Genotype-phenotype analysis of von Hippel-Lindau syndrome in Korean families: HIF-α binding site missense mutations elevate age-specific risk for CNS hemangioblastomaEmerging molecular classification in renal cell carcinoma: implications for drug development.The role of components of the chromatin modification machinery in carcinogenesis of clear cell carcinoma of the ovary (Review)VHL Type 2B gene mutation moderates HIF dosage in vitro and in vivo.Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma.Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis.Genetic evidence of a precisely tuned dysregulation in the hypoxia signaling pathway during oncogenesis.Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.RSUME inhibits VHL and regulates its tumor suppressor function.
P2860
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P2860
VHL type 2B mutations retain VBC complex form and function
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
VHL type 2B mutations retain VBC complex form and function
@ast
VHL type 2B mutations retain VBC complex form and function
@en
VHL type 2B mutations retain VBC complex form and function
@en-gb
VHL type 2B mutations retain VBC complex form and function
@nl
type
label
VHL type 2B mutations retain VBC complex form and function
@ast
VHL type 2B mutations retain VBC complex form and function
@en
VHL type 2B mutations retain VBC complex form and function
@en-gb
VHL type 2B mutations retain VBC complex form and function
@nl
altLabel
VHL Type 2B Mutations Retain VBC Complex Form and Function
@en
prefLabel
VHL type 2B mutations retain VBC complex form and function
@ast
VHL type 2B mutations retain VBC complex form and function
@en
VHL type 2B mutations retain VBC complex form and function
@en-gb
VHL type 2B mutations retain VBC complex form and function
@nl
P2093
P2860
P3181
P1433
P1476
VHL type 2B mutations retain VBC complex form and function
@en
P2093
Caroline Martz Lee
Kathryn E Hacker
W Kimryn Rathmell
P2860
P3181
P356
10.1371/JOURNAL.PONE.0003801
P407
P577
2008-01-01T00:00:00Z