Inhibition of Tat activity by the HEXIM1 protein - Test2 - elhamkhani - TriplyDB

Inhibition of Tat activity by the HEXIM1 protein

Inhibition of Tat activity by the HEXIM1 protein

http://www.wikidata.org/entity/Q21245206

about

Identification of HEXIM1 as a positive regulator of p53 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.Cellular mRNA activates transcription elongation by displacing 7SK RNA.Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case.HEXIM1 regulates 17beta-estradiol/estrogen receptor-alpha-mediated expression of cyclin D1 in mammary cells via modulation of P-TEFb A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation Non-coding RNAs regulating the transcriptional machinery.Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication.U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex.Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors.Targeting HIV transcription: the quest for a functional cure.Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells.Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells.RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation.The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency.Multiple Inhibitory Factors Act in the Late Phase of HIV-1 Replication: a Systematic Review of the Literature.Hexim1, an RNA-controlled protein hub.Prospects in Innate Immune Responses as Potential Control Strategies against Non-Primate Lentiviruses

P2860

Q24297975-2239CB00-6E9A-4480-968D-17836D021AE6 Q30438975-44088184-91E3-4D00-BBC1-CF17B9FFD9F1 Q33302108-0A28C305-3A18-4993-AD75-3C9B347032E5 Q33347964-900B0F3B-E807-4949-9B69-F1BEEE9FD599 Q33702169-345A5511-0739-4D3B-82EB-9CAC7A0E9399 Q34486331-BD2E04D3-419B-4D90-AAE5-2D89B6DA6D96 Q35072999-FD8025FA-F43A-47A2-A5E2-D31D692E866F Q35804608-1C660D85-9117-479B-AB03-2E607FEE2FC3 Q36777646-F278A1A9-E953-4438-804C-5190F334B619 Q37058515-1A9670C8-4F48-41B1-988B-0E13E7655E79 Q37183096-4BB049A6-8B82-4B99-802F-F190FFA1155B Q37368093-1DF532B4-D5AA-4A2C-A001-9E588474D18B Q38212101-C63E0567-4B06-4264-A25D-A5AC2C88B1AF Q38366762-BE5DAF0D-E166-4B4A-AFD8-2D9A372FF436 Q38557763-3A15D453-CB3B-4531-A0AF-3C6D77263D4F Q40118214-8F8F21D8-1D3B-4B37-9349-5BC790871D73 Q40238292-D75F86DA-B9F8-4EBF-8F0E-77D4CBE97B11 Q42027880-BE72E776-6E33-4208-88C5-4C5687CA5BE7 Q42117931-5A7DC66D-68D0-4216-88A5-CDB4CA207AD1 Q47555946-98926AFE-7C97-4755-99BD-9E76F2C75BD1 Q48219788-060E6888-E66F-4116-8579-8E64C0587796 Q56977004-6449A19C-EFA2-4E44-A2AE-7E31C140D676

P2860

Inhibition of Tat activity by the HEXIM1 protein

http://www.wikidata.org/entity/Q21245206

description

2005 nî lūn-bûn

@nan

2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Inhibition of Tat activity by the HEXIM1 protein

@ast

Inhibition of Tat activity by the HEXIM1 protein

@en

Inhibition of Tat activity by the HEXIM1 protein

@en-gb

Inhibition of Tat activity by the HEXIM1 protein

@nl

type

label

Inhibition of Tat activity by the HEXIM1 protein

@ast

Inhibition of Tat activity by the HEXIM1 protein

@en

Inhibition of Tat activity by the HEXIM1 protein

@en-gb

Inhibition of Tat activity by the HEXIM1 protein

@nl

prefLabel

Inhibition of Tat activity by the HEXIM1 protein

@ast

Inhibition of Tat activity by the HEXIM1 protein

@en

Inhibition of Tat activity by the HEXIM1 protein

@en-gb

Inhibition of Tat activity by the HEXIM1 protein

@nl

P1433

Q21245206-58CD8124-4271-4367-B161-6B4314709573

P1476

Q21245206-D4BE632F-69C9-476B-AC22-806F77495D42

P2093

Q21245206-04EA6AFF-0C23-467F-8DA4-399C31DAA939

Q21245206-2D79B756-98DD-44FE-8CFD-DE66419415C7

Q21245206-4CA8E74C-6D55-41CF-A703-0C0949660280

Q21245206-980D89AD-B280-48C3-B11A-EC6996376A37

Q21245206-F5D6D8D1-8B2D-432F-9759-6594A9568189

P2860

Q21245206-16F3D735-333D-496F-81C5-E5F34C108EBA

Q21245206-1BD80C45-8BD8-4E42-A270-DF00B1FBED34

Q21245206-1DA0B36E-92BC-469F-B300-35872B6DC24C

Q21245206-21AAB8E2-084F-40E8-A6D9-8D7B14CF29A7

Q21245206-261A2E10-CEC2-4333-A337-F6ACB1B5DB0F

Q21245206-2F5152A0-3E55-408F-A0E4-FFBE157E4C6F

Q21245206-325AA4DB-C102-45F5-818C-268CABD77AAB

Q21245206-36F7AD02-2977-4638-8BAC-DE3600C5DF8C

Q21245206-454D22F5-A704-49AC-8AC2-79E91B8953B6

Q21245206-4774305D-E26A-40B8-A583-665EF6775AD0

P2888

Q21245206-AC47F793-E30B-41DB-9073-3E9A8D079133

P304

Q21245206-D169E894-DBAF-4C1A-8DBD-975403ACBEA7

P31

Q21245206-26E0BA12-B7E2-405F-82B9-3E3E50B9BB13

P356

Q21245206-A2C79540-79A3-48AF-BC7C-4732290A161B

P407

Q21245206-AFD319F1-B57B-477C-A2D0-F5F6E1E89B9F

P433

Q21245206-F0EA5728-3FDF-4F92-BF7F-5E46799CA4AE

P478

Q21245206-5C353059-CB73-4E91-8F85-5BABBA50A594

P50

Q21245206-04AF10B6-111B-4DFE-BED2-730BABA470BC

Q21245206-4554992C-2ECE-4789-916F-BE992652F618

P577

Q21245206-DCEC5718-2F64-44C2-A2F5-19CC9C4D52BC

P5875

Q21245206-CE65B36F-C761-4874-B8BA-DFA7A4BC6640

P6179

Q21245206-2D711482-0A6F-4F03-9493-1FDCB9C0D9D3

P698

Q21245206-9573B7E0-390B-444A-9535-71252A4832A1

P921

Q21245206-49237F3D-6A55-476E-8732-F8EE00FDCFAC

P932

Q21245206-19D2B167-0639-4BC1-9CB9-E24FF6B8B601

P356

P1433

P1476

Inhibition of Tat activity by the HEXIM1 protein

@en

P2093

Alessandro Fraldi

http://www.w3.org/2001/XMLSchema#string

Barbara Majello

http://www.w3.org/2001/XMLSchema#string

Francesca Varrone

http://www.w3.org/2001/XMLSchema#string

Luigi Lania

http://www.w3.org/2001/XMLSchema#string

Olivier Bensaude

http://www.w3.org/2001/XMLSchema#string

P2860

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb

Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

P2888

P304

42

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/1742-4690-2-42

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P50

Annemieke A Michels

Giuliana Napolitano

P577

2005-07-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7752529

http://www.w3.org/2001/XMLSchema#string

P6179

1035692841

http://www.w3.org/2001/XMLSchema#string

P698

15992410

http://www.w3.org/2001/XMLSchema#string

P921

infectious disease

P932

1183248

http://www.w3.org/2001/XMLSchema#string